2016

Scientific Articles

unige:89645

IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death

Rutti Roch, Sabine; Howald, Cédric; Arous, Caroline; Dermitzakis, Emmanouil; ... Bouzakri, Karim

2015

Scientific Articles

unige:54924

Short Term Exposure of Beta Cells to Low Concentrations of Interleukin-1β Improves Insulin Secretion through Focal Adhesion and Actin Remodeling and Regulation of Gene Expression

Arous, Caroline; Ferreira, Pedro G; Dermitzakis, Emmanouil; Halban, Philippe A.;

2014

Scientific Articles

unige:40330	Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells	Rutti Roch, Sabine; Arous, Caroline; Nica, Alexandra C; Kanzaki, Makoto; ... Bouzakri, Karim
unige:41518	Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα	Rutti Roch, Sabine; Arous, Caroline; Schvartz, Domitille; Timper, Katharina; ... Bouzakri, Karim
unige:40331	Regenerating 1 and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats	Calderari, Sophie; Irminger, Jean-Claude; Giroix, Marie-Hélène; Ehses, Jan A; ... Homo-Delarche, Françoise
unige:39385	β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment	Halban, Philippe A.; Polonsky, Kenneth S; Bowden, Donald W; Hawkins, Meredith A; ... Weir, Gordon C

Professional Articles

unige:40332

β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment

Halban, Philippe A.; Polonsky, Kenneth S; Bowden, Donald W; Hawkins, Meredith A; ... Weir, Gordon C

2013

Scientific Articles

unige:28876	A new paradigm for improved co-ordination and efficacy of European biomedical research: taking diabetes as a model	Halban, Philippe A.; Boulton, A J M; Smith, U;
unige:28878	Autonomous and self-sustained circadian oscillators displayed in human islet cells	Pulimeno, Pamela; Mannic, Tiphaine; Sage, D; Giovannoni, Laurianne; ... Dibner, Charna
unige:28877	Cardiotrophin 1 protects beta cells from apoptosis and prevents streptozotocin-induced diabetes in a mouse model	Jiménez-González, M; Jaques, Fabienne; Rodríguez, S; Porciuncula, A; ... Barajas, M
unige:28880	Cell-type, allelic and genetic signatures in the human pancreatic beta cell transcriptome	Nica, Alexandra; Ongen, Halit; Irminger, Jean-Claude; Bosco, Domenico; ... Dermitzakis, Emmanouil
unige:28882	Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion	Arous, Caroline; Rondas, Dieter; Halban, Philippe A.;

2012

Scientific Articles

unige:26226	Bimodal impact of skeletal muscle on pancreatic β-cell function in health and disease	Plomgaard, P; Halban, Philippe A.; Bouzakri, Karim;
unige:26211	In vitro proliferation of adult human beta-cells	Rutti Roch, Sabine; Sauter, Nadine S; Bouzakri, Karim; Prazak, Richard; ... Donath, Marc Y
unige:25163	Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion	Rondas, Dieter; Tomas Catala, Alejandra Del Don; Soto Ribeiro, Martinho; Wehrle-Haller, Bernhard; Halban, Philippe A.

2011

Scientific Articles

unige:24937	Bimodal effect on pancreatic β-cells of secretory products from normal or insulin-resistant human skeletal muscle	Bouzakri, Karim; Plomgaard, Peter; Berney, Thierry; Donath, Marc Yves; ... Halban, Philippe A.
unige:25378	Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin	Rondas, Dieter; Tomas, Alejandra; Halban, Philippe A.;
unige:25370	Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto-Kakizaki (GK) rat	Giroix, M-H; Irminger, Jean-Claude; Lacraz, G; Noll, C; ... Homo-Delarche, F
unige:25369	Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells	Ellingsgaard, Helga; Hauselmann, Irina; Schuler, Beat; Habib, Abdella M; ... Donath, Marc Y

2010

Scientific Articles

unige:8785	Current status of islet cell replacement and regeneration therapy	Halban, Philippe A.; German, M. S.; Kahn, S. E.; Weir, G. C.;
unige:8727	Cytokine production by islets in health and diabetes: cellular origin, regulation and function	Donath, M. Y.; Boni-Schnetzler, Marianne; Ellingsgaard, Helga; Halban, Philippe A.; Ehses, J. A.
unige:20994	Prime time for DIAMAP: a road map for diabetes research in Europe	Halban, Philippe A.;
unige:9057	Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate	Tomas, Alejandra; Yermen, Barbara; Regazzi, Romano; Pessin, J. E.; Halban, Philippe A.

2009

Scientific Articles

unige:8793	Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function	Hammar, Eva; Tomas, Alejandra; Bosco, Domenico; Halban, Philippe A.;
unige:8956	Signaling pathways implicated in the stimulation of beta-cell proliferation by extracellular matrix	Parnaud, Géraldine; Hammar, Eva; Ribaux, Pascale; Donath, M. Y.; ... Halban, Philippe A.
unige:8655	Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion	Bouzakri, Karim; Ribaux, Pascale; Halban, Philippe A.;

Thesis supervisions

unige:1643

The role of homologous cell-cell contacts in insulin secretion

Jacques, Fabienne;

2008

Scientific Articles

unige:1431	Cell therapy for type 2 diabetes: is it desirable and can we get it?	Halban, Philippe A.;
unige:755	Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion	Jaques, Fabienne; Jousset, Hélène; Tomas Catala, Alejandra Del Don; Prost, Anne-Lise; ... Halban, Philippe A.
unige:1826	Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation	Böni-Schnetzler, Marianne; Thorne, Jeffrey; Parnaud, Géraldine; Marselli, Lorella; ... Donath, Marc Y.
unige:1825	Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14	Klinger, Sonia; Poussin, Carine; Debril, Marie-Bernard; Dolci, Wanda; ... Thorens, Bernard
unige:1828	Interleukin-6 regulates pancreatic alpha-cell mass expansion	Ellingsgaard, Helga; Ehses, Jan A.; Hammar, Eva B.; Van Lommel, Leentje; ... Donath, Marc Y.
unige:835	Munc 18-1 and granuphilin collaborate during insulin granule exocytosis	Tomas Catala, Alejandra Del Don; Meda, Paolo; Regazzi, Romano; Pessin, Jeffrey E.; Halban, Philippe A.
unige:1831	Order! Order! Order in the House! DIAMAP: a road map for European diabetes research	Halban, Philippe A.; Smith, U.;
unige:1827	Proliferation of sorted human and rat beta cells	Parnaud, Géraldine; Bosco, Domenico; Berney, Thierry; Pattou, Francois; ... Halban, Philippe A.
unige:875	Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells	Bouzakri, Karim; Ribaux, Pascale Garlonne; Tomas Catala, Alejandra Del Don; Parnaud, Géraldine; ... Halban, Philippe A.
unige:1829	Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture	Marzban, Lucy; Tomas Catala, Alejandra Del Don; Becker, Thomas C.; Rosenberg, Lawrence; ... Verchere, C Bruce
unige:1830	The right stuff: beta-cell channels, cycles, and sensors	Halban, Philippe A.;

2007

Scientific Articles

unige:9184	Comment faire renaître la cellule beta du sacrifice en sauveur	Halban, Philippe A.;
unige:8653	Differential expression of E-cadherin at the surface of rat beta-cells as a marker of functional heterogeneity	Bosco, Domenico; Rouiller, Dominique; Halban, Philippe A.;
unige:8803	Dominant-negative effects of a novel mutated Ins2 allele causes early-onset diabetes and severe beta-cell loss in Munich Ins2C95S mutant mice	Herbach, Nadja; Rathkolb, Birgit; Kemter, Elisabeth; Pichl, Lisa; ... Wanke, Ruediger
unige:8902	Dynamin is functionally coupled to insulin granule exocytosis	Min, Le; Leung, Y. M.; Tomas, Alejandra; Watson, R. T.; ... Hou, J. C.
unige:8994	Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells	Ribaux, Pascale; Ehses, J. A.; Lin-Marq, Nathalie; Carrozzino, Fabio; ... Halban, Philippe A.
unige:9105	Pro-survival role of gelsolin in mouse beta-cells	Yermen, Barbara; Tomas, Alejandra; Halban, Philippe A.;
unige:9025	The Fas pathway is involved in pancreatic beta cell secretory function	Schumann, D. M.; Maedler, Kathrin; Franklin, Isobel; Konrad, Daniel; ... Donath, M. Y.
unige:8782	The innovative medicines initiative (IMI): a shot in the arm for European diabetes research?	Halban, Philippe A.;

2006

Scientific Articles

unige:8957	Blockade of beta1 integrin-laminin-5 interaction affects spreading and insulin secretion of rat beta-cells attached on extracellular matrix	Parnaud, Géraldine; Hammar Bouveret, Eva; Rouiller, Dominique; Armanet, Mathieu Pierre Jean; ... Bosco, Domenico
unige:8784	Diabetes research investment in the European Union	Halban, Philippe A.; Ferrannini, Ele; Nerup, Jorn;
unige:8885	Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death	Marzban, Lucy; Rhodes, C. J.; Steiner, D. F.; Haataja, Leena; ... Verchere, C. B.
unige:8813	Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat	Homo-Delarche, Francoise; Calderari, Sophie; Irminger, Jean-Claude; Gangnerau, M. N.; ... Serradas, Patricia