Daali, Youssef

 
 
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2019

Scientific Articles

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CYP450 activities before and after Roux-en-Y gastric bypass: correlation with their intestinal and liver contentLloret-Linares, Célia; Daali, Youssef; Abbara, Chadi; Carette, Claire; ... Declèves, Xavier
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Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxinsSamer, Caroline Flora; Gloor, Yvonne Sylvia; Rollason Gumprecht, Victoria; Guessous, Idris; ... Daali, Youssef
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Drug-induced expression of the RNA-binding protein HuR attenuates the adaptive response to BRAF inhibition in melanomaMerat, Rastine; Bugi, Aurore; Wrobel, Ludovic; Py, Céline; ... Liaudet, Nicolas
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Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva CocktailBosilkovska Weisskopf, Marija; Magliocco, Gaëlle; Desmeules, Jules Alexandre; Samer, Caroline Flora; Daali, Youssef
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Liquid Chromatography-Tandem Mass Spectrometry Method for Ticagrelor and its Active Metabolite Determination in Human Plasma: Application to a Pharmacokinetic StudyMarsousi, Niloufar; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef;
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Perioperative intravenous low-dose ketamine for neuropathic pain after major lower back surgery: A randomized, placebo-controlled studyCzarnetzki, Christoph; Desmeules, Jules Alexandre; Tessitore, Enrico; Faundez, Antonio; ... Tramer, Martin
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Phenotyping of human CYP450 enzymes by endobiotics: current knowledge and methodological approachesMagliocco, Gaëlle; Thomas, Aurélien; Desmeules, Jules Alexandre; Daali, Youssef;
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Physiologically-based pharmacokinetic modeling for the prediction of CYP2D6-mediated gene-drug-drug interactionsStorelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef;
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Preclinical Evaluation of Safety of Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus for Use in Cancer TreatmentBovet, Luc; Samer, Caroline Flora; Daali, Youssef;
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Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modelingMagliocco, Gaëlle; Rodieux, Frédérique; Desmeules, Jules Alexandre; Samer, Caroline Flora; Daali, Youssef
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Towards personalized antithrombotic treatments: focus on P2Y12 inhibitors and direct oral anticoagulantsTerrier, Jean; Daali, Youssef; Fontana, Pierre; Csajka, Chantal; Reny, Jean-Luc
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Variables of interest to predict glomerular filtration rate in preterm newborns in the first days of lifeWilhelm-Bals, Alexandra Marina; Combescure, Christophe; Chehade, Hassib; Daali, Youssef; Parvex, Paloma Maria

Thesis supervisions

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Proteomic phenotyping of CNS cells exposed to inflammatory stimuli and opioidsDozio, Vito;

2018

Scientific Articles

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Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical PerspectivesStorelli, Flavia; Samer, Caroline Flora; Reny, Jean-Luc; Desmeules, Jules Alexandre; Daali, Youssef
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Genotype-sensitive reversible and time-dependent CYP2D6 inhibition in human liver microsomesStorelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef;
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Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active MetabolitesMarsousi, Niloufar; Daali, Youssef; Fontana, Pierre; Reny, Jean-Luc; ... Samer, Caroline Flora
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Phenotypic Assessment of Drug Metabolic Pathways and P-Glycoprotein in Patients Treated With Antidepressants in an Ambulatory SettingLloret-Linares, Célia; Bosilkovska Weisskopf, Marija; Daali, Youssef; Gex-Fabry, Marianne; ... Besson, Marie
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Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp softwareMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
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Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case reportAebischer, Gaspard; Ing Lorenzini, Kuntheavy; Tomala, Simon; Desmeules, Jules Alexandre; ... Samer, Caroline Flora
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Therapeutic Drug Monitoring of Busulfan for the Management of Pediatric Patients: Cross-Validation of Methods and Long-Term PerformanceChoong, Eva; Uppugunduri, Chakradhara Rao Satyanarayana; Marino, Denis; Kuntzinger, Mélanie; ... Ansari Djaberi, Marc Georges

Thesis supervisions

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Understanding and predicting the association of intrinsic and extrinsic factors of pharmacokinetic variability in the context of precision medicine: impact of genetic polymorphisms on CYP2D6-mediated drug-drug interactionsStorelli, Flavia;

2017

Scientific Articles

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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferasesRomand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge
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Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study)Lloret-Linares, Célia; Daali, Youssef; Chevret, Sylvie; Nieto, Isabelle; ... Bellivier, Frank
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Hepatocyte Concentrations of Indocyanin Green (ICG) Reflects Transfer Rates Across Membrane TransportersCusin, Fabien; Azevedo, Liliana; Bonnaventure, Pierre; Desmeules, Jules Alexandre; ... Pastor, Catherine
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Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactionsStorelli, Flavia; Matthey, Alain; Lenglet, Sébastien; Thomas, Aurélien; ... Daali, Youssef
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Plasma concentrations of transdermal fentanyl and buprenorphine in pigs (Sus scrofa domesticus)Osorio Lujan, Suzanne; Habre, Walid; Daali, Youssef; Pan, Zhaoxin; Kronen, Peter W
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Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective studyLloret-Linares, Célia; Rollason Gumprecht, Victoria; Ing Lorenzini, Kuntheavy; Samer, Caroline Flora; ... Besson, Marie
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The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell TransplantationUppugunduri, Chakradhara Rao S; Storelli, Flavia; Mlakar, Vid; Huezo-Diaz Curtis, Patricia; ... Ansari Djaberi, Marc Georges
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Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized MedicineMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
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Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the futureDarwich, A S; Ogungbenro, K; Vinks, A A; Powell, J R; ... Rostami-Hodjegan, A

2016

Scientific Articles

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An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposureSpaggiari, Dany; Daali, Youssef; Rudaz, Serge;
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Aspirin response: Differences in serum thromboxane B2 levels between clinical studiesBrun, Charlotte; Daali, Youssef; Combescure, Christophe; Zufferey Bakos, Anne; ... Frelinger, Andrew L (3rd)
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Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approachMarsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef
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Detection of busulfan adducts on proteinsAcosta Martin, Adelina Elena; Antinori Malaspina, Paola; Uppugunduri Satyanarayana, Chakradhara Rao; Daali, Youssef; ... Lescuyer, Pierre
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Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling MethodBosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Daali, Youssef
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Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosisSeredenin, Tamara; Nayernia, Zeynab; Sorce, Silvia; Maghzal, Ghassan J; ... Jaquet, Vincent
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Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cellsMarsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef
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Pharmacogenomics of Oral Antithrombotic DrugsStorelli, Flavia; Daali, Youssef; Desmeules, Jules Alexandre; Reny, Jean-Luc; Fontana, Pierre
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Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic DefectIng Lorenzini, Kuntheavy; Daali, Youssef; Fontana, Pierre; Desmeules, Jules Alexandre; Samer, Caroline Flora
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Severe Vincristine-Induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case StudyBosilkovska Weisskopf, Marija; Ing Lorenzini, Kuntheavy; Uppugunduri Satyanarayana, Chakradhara Rao; Desmeules, Jules Alexandre; ... Escher, Monica
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The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesiaRalvenius, William T; Acuña, Mario A; Benke, Dietmar; Matthey, Alain; ... Besson, Marie
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