Daali, Youssef

 
 
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2017

Scientific Articles

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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferasesRomand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer Fahem, Caroline Flora; ... Rudaz, Serge
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Hepatocyte Concentrations of Indocyanin Green (ICG) Reflects Transfer Rates Across Membrane TransportersCusin, Fabien; Azevedo, Liliana; Bonnaventure, Pierre; Desmeules, Jules Alexandre; ... Pastor, Catherine
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Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactionsStorelli, Flavia; Matthey, Alain; Lenglet, Sébastien; Thomas, A; ... Daali, Youssef
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Plasma concentrations of transdermal fentanyl and buprenorphine in pigs (Sus scrofa domesticus)Osorio Lujan, Suzanne; Habre, Walid; Daali, Youssef; Pan, Zhaoxin; Kronen, Peter W
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Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp softwareMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
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Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective studyLloret-Linares, Célia; Rollason Gumprecht, Victoria; Ing Lorenzini, Kuntheavy; Samer Fahem, Caroline Flora; ... Besson, Marie
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The Association of Combined GSTM1 and CYP2C9 Genotype Status with the Occurrence of Hemorrhagic Cystitis in Pediatric Patients Receiving Myeloablative Conditioning Regimen Prior to Allogeneic Hematopoietic Stem Cell TransplantationUppugunduri, Chakradhara Rao S; Storelli, Flavia; Mlakar, Vid; Huezo-Diaz Curtis, Patricia; ... Ansari Djaberi, Marc Georges
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Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized MedicineMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
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Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the futureDarwich, A S; Ogungbenro, K; Vinks, A A; Powell, J R; ... Rostami-Hodjegan, A

2016

Scientific Articles

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An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposureSpaggiari, Dany; Daali, Youssef; Rudaz, Serge;
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Aspirin response: Differences in serum thromboxane B2 levels between clinical studiesBrun, Charlotte; Daali, Youssef; Combescure, Christophe; Zufferey Bakos, Anne; ... Frelinger, Andrew L (3rd)
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Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approachMarsousi, Niloufar; Samer Fahem, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef
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Detection of busulfan adducts on proteinsAcosta Martin, Adelina Elena; Antinori Malaspina, Paola; Uppugunduri Satyanarayana, Chakradhara Rao; Daali, Youssef; ... Lescuyer, Pierre
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Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling MethodBosilkovska Weisskopf, Marija; Samer Fahem, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Daali, Youssef
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Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosisSeredenin, Tamara; Nayernia, Zeynab; Sorce, Silvia; Maghzal, Ghassan J; ... Jaquet, Vincent
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Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cellsMarsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef
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Pharmacogenomics of Oral Antithrombotic DrugsStorelli, Flavia; Daali, Youssef; Desmeules, Jules Alexandre; Reny, Jean-Luc; Fontana, Pierre
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Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic DefectIng Lorenzini, Kuntheavy; Daali, Youssef; Fontana, Pierre; Desmeules, Jules Alexandre; Samer Fahem, Caroline Flora
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Severe Vincristine-Induced Neuropathic Pain in a CYP3A5 Nonexpressor With Reduced CYP3A4/5 Activity: Case StudyBosilkovska Weisskopf, Marija; Ing Lorenzini, Kuntheavy; Uppugunduri Satyanarayana, Chakradhara Rao; Desmeules, Jules Alexandre; ... Escher, Monica
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The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesiaRalvenius, William T; Acuña, Mario A; Benke, Dietmar; Matthey, Alain; ... Besson, Marie

2014

Scientific Articles

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A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologiesSpaggiari, Dany; Geiser, Laurent; Daali, Youssef; Rudaz, Serge;
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Antiplatelet Therapy: Targeting the TxA2 PathwayFontana, Pierre; Zufferey Bakos, Anne; Daali, Youssef; Reny, Jean-Luc;
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Geneva Cocktail for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood SpotsBosilkovska Weisskopf, Marija; Samer Fahem, Caroline Flora; Deglon, Julien; Rebsamen, Michela; ... Daali, Youssef
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Incorporation of Flurbiprofen in a 4-Drug Cytochrome P450 Phenotyping CocktailBosilkovska Weisskopf, Marija; Clement, Mallorie; Dayer, Pierre; Desmeules, Jules Alexandre; Daali, Youssef
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Phenotyping of CYP450 in human liver microsomes using the cocktail approachSpaggiari, Dany; Geiser, Laurent; Daali, Youssef; Rudaz, Serge;
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Prediction by pharmacogenetics of safety and efficacy of non-steroidal anti- inflammatory drugs: a reviewRollason Gumprecht, Victoria; Samer Fahem, Caroline Flora; Daali, Youssef; Desmeules, Jules Alexandre;
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Prediction of Metabolic Interactions With Oxycodone via CYP2D6 and CYP3A Inhibition Using a Physiologically Based Pharmacokinetic ModelMarsousi, Niloufar; Daali, Youssef; Rudaz, Serge; Almond, L; ... Samer Fahem, Caroline Flora
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Role of paraoxonase-1 in CYP2C19 loss-of-function carriersDaali, Youssef; Reny, Jean-Luc; Fontana, Pierre;
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Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasmaBosilkovska Weisskopf, Marija; Deglon, Julien; Samer Fahem, Caroline Flora; Walder, Bernhard; ... Daali, Youssef
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The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantationUppugunduri Satyanarayana, Chakradhara Rao; Rezgui, M; Diaz, PH; Tyagi, Anuj Kumar; ... Ansari Djaberi, Marc Georges
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Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activityBouatou, Yassine; Samer Fahem, Caroline Flora; Ing Lorenzini, Kuntheavy Roseline; Daali, Youssef; ... Escher, Monica

2013

Scientific Articles

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Antihyperalgesic Effect of the GABA(A) Ligand Clobazam in a Neuropathic Pain Model in Mice: A Pharmacokinetic-Pharmacodynamic StudyBesson, Marie; Daali, Youssef; Di Lio, Alessandra; Dayer, Pierre; ... Desmeules, Jules Alexandre
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Applications of CYP450 Testing in the Clinical SettingSamer Fahem, Caroline Flora; Ing Lorenzini, Kuntheavy; Rollason Gumprecht, Victoria; Daali, Youssef; Desmeules, Jules Alexandre
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Dual reuptake inhibitor milnacipran and spinal pain pathways in fibromyalgia patients: a randomized, double-blind, placebo-controlled trialMatthey, Alain; Cedraschi, Christine; Piguet, Valérie; Besson, Marie; ... Desmeules, Jules Alexandre
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Evidence of Drug-Drug Interactions through Uptake and Efflux Transport Systems in Rat Hepatocytes: Implications for Cellular Concentrations of Competing DrugsDaali, Youssef; Millet, Philippe; Dayer, Pierre; Pastor, Catherine;
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Influence of CYP2D6 activity on pre-emptive analgesia by the N-methyl-D-aspartate antagonist dextromethorphan in a randomized controlled trial of acute painEhret, Georg Benedikt; Daali, Youssef; Chabert, Jocelyne; Rebsamen, Michela; ... Desmeules, Jules Alexandre
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Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic modelSchenkel, Fanny; Csajka, Chantal; Baglivo, Edoardo; Kondo Ostreicher, Mitsuko; ... Daali, Youssef
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Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative propertiesKhanicheh, Elham; Qi, Yue; Xie, Aris; Mitterhuber, Martina; ... Kaufmann, Beat A
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Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteersAncrenaz, Virginie; Deglon, Julien; Samer Fahem, Caroline Flora; Staub, Christian Olivier; ... Desmeules, Jules Alexandre
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Role of P-glycoprotein in the uptake/efflux transport of oral vitamin K antagonists and rivaroxaban through the Caco-2 cell modelGschwind, Liliane; Rollason Gumprecht, Victoria; Daali, Youssef; Bonnabry, Pascal; ... Desmeules, Jules Alexandre

2012

Scientific Articles

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A simplified method for busulfan monitoring using dried blood spot in combination with liquid chromatography/tandem mass spectrometryAnsari Djaberi, Marc Georges; Uppugunduri Satyanarayana, Chakradhara Rao; Deglon, Julien; Théorêt, Yves; ... Daali, Youssef
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Analgesics in patients with hepatic impairment: pharmacology and clinical implicationsBosilkovska Weisskopf, Marija; Walder, Bernhard; Besson, Marie; Daali, Youssef; Desmeules, Jules Alexandre
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Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysisReny, Jean-Luc; Combescure, Christophe; Daali, Youssef; Fontana, Pierre;
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Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infectionGirardin, François; Daali, Youssef; Gex-Fabry, Marianne; Rebsamen, Michela; ... Desmeules, Jules Alexandre
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NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretionLi, Ning; Li, Bin; Brun, Thierry; Deffert-Delbouille, Christine; ... Maechler, Pierre
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Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spotDaali, Youssef; Samer Fahem, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Desmeules, Jules Alexandre
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Pharmacokinetic-pharmacodynamic modelling of opioids in healthy human volunteers. A minireviewIng Lorenzini, Kuntheavy; Daali, Youssef; Dayer, Pierre; Desmeules, Jules Alexandre;
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