Daali, Youssef

 
 
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2016

Scientific Articles

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An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposureSpaggiari, Dany; Daali, Youssef; Rudaz, Serge;
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Aspirin response: Differences in serum thromboxane B2 levels between clinical studiesBrun, Charlotte; Daali, Youssef; Combescure, Christophe; Zufferey Bakos, Anne; ... Frelinger, Andrew L (3rd)
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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferasesRomand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge
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Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approachMarsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef
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Detection of busulfan adducts on proteinsAcosta Martin, Adelina Elena; Antinori Malaspina, Paola; Uppugunduri Satyanarayana, Chakradhara Rao; Daali, Youssef; ... Lescuyer, Pierre
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Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling MethodBosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Daali, Youssef
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Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosisSeredenin, Tamara; Nayernia, Zeynab; Sorce, Silvia; Maghzal, Ghassan J; ... Jaquet, Vincent
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Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cellsMarsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef
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Pharmacogenomics of Oral Antithrombotic DrugsStorelli, Flavia; Daali, Youssef; Desmeules, Jules Alexandre; Reny, Jean-Luc; Fontana, Pierre
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Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic DefectIng Lorenzini, Kuntheavy; Daali, Youssef; Fontana, Pierre; Desmeules, Jules Alexandre; Samer, Caroline Flora
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Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective studyLloret-Linares, Célia; Rollason Gumprecht, Victoria; Ing Lorenzini, Kuntheavy; Samer, Caroline Flora; ... Besson, Marie
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The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesiaRalvenius, William T; Acuña, Mario A; Benke, Dietmar; Matthey, Alain; ... Besson, Marie

2014

Scientific Articles

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A cocktail approach for assessing the in vitro activity of human cytochrome P450s: An overview of current methodologiesSpaggiari, Dany; Geiser, Laurent; Daali, Youssef; Rudaz, Serge;
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Antiplatelet Therapy: Targeting the TxA2 PathwayFontana, Pierre; Zufferey Bakos, Anne; Daali, Youssef; Reny, Jean-Luc;
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Geneva Cocktail for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood SpotsBosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Rebsamen, Michela; ... Daali, Youssef
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Incorporation of Flurbiprofen in a 4-Drug Cytochrome P450 Phenotyping CocktailBosilkovska Weisskopf, Marija; Clement, Mallorie; Dayer, Pierre; Desmeules, Jules Alexandre; Daali, Youssef
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Phenotyping of CYP450 in human liver microsomes using the cocktail approachSpaggiari, Dany; Geiser, Laurent; Daali, Youssef; Rudaz, Serge;
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Prediction by pharmacogenetics of safety and efficacy of non-steroidal anti- inflammatory drugs: a reviewRollason Gumprecht, Victoria; Samer, Caroline Flora; Daali, Youssef; Desmeules, Jules Alexandre;
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Prediction of Metabolic Interactions With Oxycodone via CYP2D6 and CYP3A Inhibition Using a Physiologically Based Pharmacokinetic ModelMarsousi, Niloufar; Daali, Youssef; Rudaz, Serge; Almond, L; ... Samer, Caroline Flora
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Role of paraoxonase-1 in CYP2C19 loss-of-function carriersDaali, Youssef; Reny, Jean-Luc; Fontana, Pierre;
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Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasmaBosilkovska Weisskopf, Marija; Deglon, Julien; Samer, Caroline Flora; Walder, Bernhard; ... Daali, Youssef
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The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantationUppugunduri Satyanarayana, Chakradhara Rao; Rezgui, M; Diaz, PH; Tyagi, Anuj Kumar; ... Ansari Djaberi, Marc Georges
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Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activityBouatou, Yassine; Samer Fahem, Caroline Flora; Ing Lorenzini, Kuntheavy Roseline; Daali, Youssef; ... Escher, Monica

2013

Scientific Articles

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Antihyperalgesic Effect of the GABA(A) Ligand Clobazam in a Neuropathic Pain Model in Mice: A Pharmacokinetic-Pharmacodynamic StudyBesson, Marie; Daali, Youssef; Di Lio, Alessandra; Dayer, Pierre; ... Desmeules, Jules Alexandre
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Applications of CYP450 Testing in the Clinical SettingSamer, Caroline Flora; Ing Lorenzini, Kuntheavy; Rollason Gumprecht, Victoria; Daali, Youssef; Desmeules, Jules Alexandre
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Dual reuptake inhibitor milnacipran and spinal pain pathways in fibromyalgia patients: a randomized, double-blind, placebo-controlled trialMatthey, Alain; Cedraschi, Christine; Piguet, Valérie; Besson, Marie; ... Desmeules, Jules Alexandre
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Evidence of Drug-Drug Interactions through Uptake and Efflux Transport Systems in Rat Hepatocytes: Implications for Cellular Concentrations of Competing DrugsDaali, Youssef; Millet, Philippe; Dayer, Pierre; Pastor, Catherine;
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Influence of CYP2D6 activity on pre-emptive analgesia by the N-methyl-D-aspartate antagonist dextromethorphan in a randomized controlled trial of acute painEhret, Georg Benedikt; Daali, Youssef; Chabert, Jocelyne; Rebsamen, Michela; ... Desmeules, Jules Alexandre
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Intraocular penetration of penciclovir after oral administration of famciclovir: a population pharmacokinetic modelSchenkel, Fanny; Csajka, Chantal; Baglivo, Edoardo; Kondo Ostreicher, Mitsuko; ... Daali, Youssef
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Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative propertiesKhanicheh, Elham; Qi, Yue; Xie, Aris; Mitterhuber, Martina; ... Kaufmann, Beat A
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Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteersAncrenaz, Virginie; Deglon, Julien; Samer, Caroline Flora; Staub, Christian Olivier; ... Desmeules, Jules Alexandre
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Role of P-glycoprotein in the uptake/efflux transport of oral vitamin K antagonists and rivaroxaban through the Caco-2 cell modelGschwind, Liliane; Rollason Gumprecht, Victoria; Daali, Youssef; Bonnabry, Pascal; ... Desmeules, Jules Alexandre

2012

Scientific Articles

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A simplified method for busulfan monitoring using dried blood spot in combination with liquid chromatography/tandem mass spectrometryAnsari Djaberi, Marc Georges; Uppugunduri Satyanarayana, Chakradhara Rao; Deglon, Julien; Théorêt, Yves; ... Daali, Youssef
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Analgesics in patients with hepatic impairment: pharmacology and clinical implicationsBosilkovska Weisskopf, Marija; Walder, Bernhard; Besson, Marie; Daali, Youssef; Desmeules, Jules Alexandre
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Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysisReny, Jean-Luc; Combescure, Christophe; Daali, Youssef; Fontana, Pierre;
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Liver kidney microsomal type 1 antibodies reduce the CYP2D6 activity in patients with chronic hepatitis C virus infectionGirardin, François; Daali, Youssef; Gex-Fabry, Marianne; Rebsamen, Michela; ... Desmeules, Jules Alexandre
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NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretionLi, Ning; Li, Bin; Brun, Thierry; Deffert-Delbouille, Christine; ... Maechler, Pierre
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Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spotDaali, Youssef; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Desmeules, Jules Alexandre
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Pharmacokinetic-pharmacodynamic modelling of opioids in healthy human volunteers. A minireviewIng Lorenzini, Kuntheavy; Daali, Youssef; Dayer, Pierre; Desmeules, Jules Alexandre;
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Serotonin syndrome following drug-drug interactions and CYP2D6 and CYP2C19 genetic polymorphisms in an HIV-infected patientLorenzini, Kuntheavy I.; Calmy, Alexandra; Ambrosioni Czyrko, Juan; Assouline, Benjamin; ... Samer, Caroline Flora
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