2020

Scientific Articles

unige:136484

Identification of anti-mycobacterium and anti-legionella compounds with potential distinctive structural scaffolds from an HD-PBL using phenotypic screens in amoebae host models

Hanna, Nabil; Kicka, Sébastien; Chiriano, Gianpaolo; Harrison, Christopher; ... Soldati, Thierry

2019

Scientific Articles

unige:133092

Antimycobacterial activity in a single-cell infection assay of ellagitannins from Combretum aculeatum and their bioavailable metabolites

Diop, El Hadji Assane; Ferreira Queiroz, Emerson; Marcourt, Laurence; Kicka, Sébastien; ... Wolfender, Jean-Luc

Preprints

unige:137618

Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress

Hanna, Nabil; Burdet, F.; Melotti, Astrid; Bosmani, Cristina; ... Soldati, Thierry

2018

Scientific Articles

unige:103009	Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets	Trofimov, Valentin; Kicka, Sébastien; Mucaria, Sabrina; Hanna, Nabil; ... Soldati, Thierry
unige:103010	Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activity	Diop, ElHadji Assane; Queiroz, Emerson Ferreira; Kicka, Sébastien; Rudaz, Serge; ... Wolfender, Jean-Luc

Preprints

unige:112884

Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host models

Kicka, Sébastien; Hanna, Nabil; Chiriano, Gianpaolo; Harrison, Christopher; ... Soldati, Thierry

2017

Scientific Articles

unige:96991	Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model	Ouertatani, Hajer; Kicka, Sébastien; Chiriano, Gianpaolo; Harrison, Christopher F; ... Cosson, Pierre
unige:96994	Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner	Cardenal-Munoz, Elena; Arafah, Sonia; Lopez Jimenez, Ana Teresa; Kicka, Sébastien; ... Soldati, Thierry

2016

Scientific Articles

unige:83859	In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA	Slepikas, Liudas; Chiriano, Gianpaolo; Perozzo, Remo; Tardy, Sébastien; ... Scapozza, Leonardo
unige:87792	Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond	Van Voorhis, Wesley C; Kicka, Sébastien; Soldati, Thierry; Trofimov, Valentin; Abla, Nada

2015

Scientific Articles

unige:76665	Adrenergic antagonists restrict replication of Legionella	Harrison, Christopher F; Kicka, Sébastien; Kranjc Pietrucci, Agata; Finsel, Ivo; ... Hilbi, Hubert
unige:76776	Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila	Harrison, Christopher F.; Chiriano, Gianpaolo; Finsel, Ivo; Manske, Christian; ... Hilbi, Hubert

2014

Scientific Articles

unige:38876

Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system

Kicka, Sébastien; Trofimov, Valentin; Harrison, Christopher; Ouertatani, Hajer; ... Soldati, Thierry

2013

Scientific Articles

unige:30319	Exploring Anti-Bacterial Compounds against Intracellular Legionella	Harrison, Christopher F; Kicka, Sébastien; Trofimov, Valentin; Berschl, Kathrin; ... Hilbi, Hubert
unige:28552	Setting up and monitoring an infection of Dictyostelium discoideum with mycobacteria	Arafah, Sonia; Kicka, Sébastien; Trofimov, Valentin; Hagedorn, Monica; ... Soldati, Thierry