Matthey, Alain

 
 
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2021

Doctoral Thesis

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Exploration du rôle de la modulation GABAergique dans la transmission de la douleur chez l'homme : Effet du modulateur allostérique GABAA N-desméthylclobazam sur la sensibilisation centrale; étude pharmacodynamique et pharmacocinétique chez le volontaire sainMatthey, Alain;

2020

Scientific Articles

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GABAergic modulation of secondary hyperalgesia: A randomized controlled 4-way crossover trial with the α2-subunit preferring GABA positive allosteric modulator, N-desmethyl-clobazam in healthy volunteersMatthey, Alain; Daali, Youssef; Curtin, François; Poncet, Antoine; ... Besson, Marie
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Safety and immunogenicity of the epicutaneous reactivation of pertussis toxin immunity in healthy adults: a phase I, randomized, double-blind, placebo-controlled trialChatzis, Olga; Blanchard Rohner, Géraldine; Mondoulet, L; Pelletier, B; ... Siegrist, Claire-Anne

2017

Scientific Articles

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Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactionsStorelli, Flavia; Matthey, Alain; Lenglet, Sébastien; Thomas, Aurélien; ... Daali, Youssef

2016

Scientific Articles

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Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe : Preliminary ReportAgnandji, Selidji T; Csaki Huttner, Angela; Zinser, Madeleine E; Njuguna, Patricia; ... Siegrist, Claire-Anne
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The clobazam metabolite N-desmethyl clobazam is an α2 preferring benzodiazepine with an improved therapeutic window for antihyperalgesiaRalvenius, William T; Acuña, Mario A; Benke, Dietmar; Matthey, Alain; ... Besson, Marie

2015

Scientific Articles

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A phase IIa randomised clinical study of GNbAC1, a humanised monoclonal antibody against the envelope protein of multiple sclerosis-associated endogenous retrovirus in multiple sclerosis patientsDerfuss, Tobias; Curtin, François; Guebelin, Claudia; Bridel, Claire; ... Lalive d'Epinay, Patrice
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A phase IIa randomized clinical study testing GNbAC1, a humanized monoclonal antibody against the envelope protein of multiple sclerosis associated endogenous retrovirus in multiple sclerosis patients - a twelve month follow-upDerfuss, Tobias; Curtin, François; Guebelin, Claudia; Bridel, Claire; ... Lalive d'Epinay, Patrice
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GABAergic modulation in central sensitization in humans: a randomized placebo-controlled pharmacokinetic-pharmacodynamic study comparing clobazam with clonazepam in healthy volunteersBesson, Marie; Matthey, Alain; Daali, Youssef; Poncet, Antoine; ... Desmeules, Jules Alexandre
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P-glycoprotein: a clue to vitamin K antagonist stabilizationGschwind, Liliane; Rollason, Victoria; Boehlen, Françoise; Rebsamen, Michela; ... Desmeules, Jules Alexandre
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The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trialCsaki Huttner, Angela; Dayer, Julie-Anne; Yerly Ferrillo, Sabine; Combescure, Christophe; ... Siegrist, Claire-Anne

2013

Scientific Articles

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Dual reuptake inhibitor milnacipran and spinal pain pathways in fibromyalgia patients: a randomized, double-blind, placebo-controlled trialMatthey, Alain; Cedraschi, Christine; Piguet, Valérie; Besson, Marie; ... Desmeules, Jules Alexandre
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Impact of CYP2C9 polymorphisms on the vulnerability to pharmacokinetic drug-drug interactions during acenocoumarol treatmentGschwind, Liliane; Rollason, Victoria; Boehlen, Françoise; Rebsamen, Michela; ... Desmeules, Jules Alexandre
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