Herrera, Pedro Luis

 
 
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2017

Scientific Articles

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Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and ArxChakravarthy, Harini; Gu, Xueying; Enge, Martin; Dai, Xiaoqing; ... Kim, Seung K.
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Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasisDamond, Nicolas; Thorel, Fabrizio; Kim, Seung K.; Herrera, Pedro Luis;
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Insulin and Glucagon: Partners for LifeHolst, Jens Juul; Holland, William; Gromada, Jesper; Lee, Young; ... Herrera, Pedro Luis
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Mafa Enables Pdx1 to Effectively Convert Pancreatic Islet Progenitors and Committed Islet α-Cells into β-Cells in VivoMatsuoka, Taka-aki; Kawashima, Satoshi; Miyatsuka, Takeshi; Sasaki, Shugo; ... Shimomura, Iichiro
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Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in miceda Silva Xavier, Gabriela; Mondragon, Angeles; Mourougavelou, Vishnou; Cruciani-Guglielmacci, Céline; ... Rutter, Guy A
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Pancreatic α Cell-Derived Glucagon-Related Peptides Are Required for β Cell Adaptation and Glucose HomeostasisTraub, Shuyang; Meier, Daniel T.; Schulze, Friederike; Dror, Erez; ... Donath, Marc Y.

2016

Scientific Articles

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A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-CellsCigliola, Valentina; Populaire, Celine; Pierri, Ciro L; Deutsch, Samuel; ... Meda, Paolo
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Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persistDamond, Nicolas; Thorel, Fabrizio; Moyers, Julie S; Charron, Maureen J; ... Herrera, Pedro Luis
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Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon productionSemplici, Francesca; Mondragon, Angeles; Macintyre, Benedict; Madeyski-Bengston, Katja; ... Rutter, Guy A
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Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-CellsPaul, Leena; Walker, Emily M; Drosos, Yiannis; Cyphert, Holly A; ... Sosa-Pineda, Beatriz
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Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversionChera, Simona; Herrera, Pedro Luis;
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Stress-impaired transcription factor expression and insulin secretion in transplanted human isletsDai, Chunhua; Kayton, Nora S; Shostak, Alena; Poffenberger, Greg; ... Powers, Alvin C
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Stress-induced adaptive islet cell identity changesCigliola, Valentina; Thorel, Fabrizio; Chera, Simona; Herrera, Pedro Luis;

Thesis supervisions

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Differentiation dynamics, postnatal fate and plasticity potential of murine embryonic pancreatic endocrine cellsBaronnier Caffe, Delphine;
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Pancreatic islet cell signaling in homeostatic conditions and in regeneration during diabetesCigliola, Valentina;

2015

Scientific Articles

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A standardized method for in vivo mouse pancreas imaging and semiquantitative β cell mass measurement by dual isotope SPECT.Mathijs, Iris; Xavier, Catarina; Peleman, Cindy; Caveliers, Vicky; ... Bouwens, Luc
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Connective Tissue Growth Factor Modulates Adult β-Cell Maturity and Proliferation to Promote β-Cell Regeneration in MiceRiley, Kimberly G; Pasek, Raymond C; Maulis, Matthew F; Peek, Jennifer; ... Gannon, Maureen
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Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD–scid IL-2rgnull RIP-DTR mice engrafted with human isletsBortell, Rita; Yang, Chaoxing; Loehn, Matthias; Jurczyk, Agata; ... Harlan, David
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LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemiaSun, Gao; da Silva Xavier, Gabriela; Gorman, Tracy; Priest, Claire; ... Rutter, Guy A.
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Role of the type 2 diabetes genome-wide association studies gene SLC30A8 in the pancreatic alpha cellSolomou, A. M.; Meur, G.; Bellomo, E. A.; Hodson, D. J.; ... Rutter, G. A.
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Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in miceVinet, Laurent; Lamprianou, Smaragda; Babic, Andréj; Lange, Norbert; ... Meda, Paolo
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The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon SecretionSolomou, Antonia; Meur, Gargi; Bellomo, Elisa; Hodson, David J; ... Rutter, Guy A

Thesis supervisions

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Dual role for glucagon-producing α-cells in diabetes: contribution to disease progression and to restoration of insulin productionDamond, Nicolas;

2014

Scientific Articles

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Argonaute2 mediates compensatory expansion of the pancreatic β cellTattikota, Sudhir G; Rathjen, Thomas; McAnulty, Sarah J; Wessels, Hans-Hermann; ... Poy, Matthew N
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Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producersChera, Simona; Baronnier Caffe, Delphine; Ghila, Luiza Mihaela; Cigliola, Valentina; ... Herrera, Pedro Luis

Professional Articles

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Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetesChow, Samuel Z; Speck, Madeleine; Yoganathan, Piriya; Nackiewicz, Dominika; ... Ehses, Jan A

2013

Scientific Articles

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An Essential Role for Insulin and IGF1 Receptors in Regulating Sertoli Cell Proliferation, Testis Size, and FSH Action in MicePitetti, Jean-Luc; Calvel, Pierre; Zimmermann, Céline; Conne, Béatrice; ... Nef, Serge
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In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretionHuang, Ya-Chi; Rupnik, Marjan S; Karimian, Negar; Herrera, Pedro Luis; ... Gaisano, Herbert Y
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Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in micePitetti, Jean-Luc; Calvel, Pierre; Romero, Yannick; Conne, Béatrice; ... Nef, Serge
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Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulinFujikawa, Teppei; Berglund, Eric D; Patel, Vishal R; Ramadori, Giorgio; ... Coppari, Roberto
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Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes developmentSupale, Sachin; Thorel, Fabrizio; Merkwirth, Carsten; Gjinovci, Asllan; ... Maechler, Pierre
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Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identitySchaffer, Ashleigh E; Taylor, Brandon L; Benthuysen, Jacqueline R; Liu, Jingxuan; ... Sander, Maike
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Nogo-A downregulation improves insulin secretion in miceBonal, Claire Brune; Baronnier Caffe, Delphine; Pot Kreis, Caroline; Benkhoucha, Mahdia; ... Herrera, Pedro Luis
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UCP2 regulates the glucagon response to fasting and starvationAllister, Emma M; Robson-Doucette, Christine A; Prentice, Kacey J; Hardy, Alexandre B; ... Wheeler, Michael B

2012

Scientific Articles

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PPARβ/δ affects pancreatic β cell mass and insulin secretion in miceIglesias, José; Barg, Sebastian; Vallois, David; Lahiri, Shawon; ... Wahli, Walter
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The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and β cell function in miceZhang, Ye; Xie, Zhifang; Zhou, Luting; Li, Ling; ... Zhang, Weiping J

2011

Scientific Articles

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Context-specific α- to-β-cell reprogramming by forced Pdx1 expressionYang, Yu-Ping; Thorel, Fabrizio; Boyer, Daniel F; Herrera, Pedro Luis; Wright, Christopher V E
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Dicer is required for haploid male germ cell differentiation in miceKorhonen, Hanna M; Meikar, Oliver; Yadav, Ram Prakash; Papaioannou, Marilena D; ... Kotaja, Noora
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Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchymeSylvestersen, Kathrine B; Herrera, Pedro Luis; Serup, Palle; Rescan, Claude;
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In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in miceHu He, Kai Hui; Lorenzo, Petra I; Brun, Thierry; Jimenez Moreno, Carmen M; ... Gauthier, Benoit R
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Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligandsVirostko, John; Henske, Joseph; Vinet, Laurent; Lamprianou, Smaragda; ... Powers, Alvin C
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Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult miceThorel, Fabrizio; Damond, Nicolas; Chera, Simona; Wiederkehr, Andreas; ... Herrera, Pedro Luis
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Progenitor cell domains in the developing and adult pancreasKopp, Janel L; Dubois, Claire L; Hao, Ergeng; Thorel, Fabrizio; ... Sander, Maike
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Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearanceSchaffer, Ashleigh E; Yang, Almira J; Thorel, Fabrizio; Herrera, Pedro Luis; Sander, Maike
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β-cell regeneration: the pancreatic intrinsic facultyDesgraz, Renaud; Bonal, Claire Brune; Herrera, Pedro Luis;
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