Rudaz, Serge

 
 
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2018

Scientific Articles

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Applicability of supercritical fluid chromatography–mass spectrometry to metabolomics. I – Optimization of separation conditions for the simultaneous analysis of hydrophilic and lipophilic substancesDesfontaine, Vincent; Losacco, Gioacchino Luca; Gagnebin, Yoric; Pezzatti, Julian; ... Guillarme, Davy
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Determination of 16 antineoplastic drugs by capillary electrophoresis with UV detection: Applications in quality controlGuichard, Nicolas; Ogereau, Marie; Falaschi, Ludivine; Rudaz, Serge; ... Fleury-Souverain, Sandrine
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Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active MetabolitesMarsousi, Niloufar; Daali, Youssef; Fontana, Pierre; Reny, Jean-Luc; ... Samer, Caroline Flora
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Implementation of a generic liquid chromatographic methoddevelopment workflow: Application to the analysis ofphytocannabinoids and Cannabis sativa extractsFekete, Szabolcs; Sadat-Noorbakhsh, Vida; Schelling, Cédric; Molnar, Imre; ... Veuthey, Jean-Luc
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Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp softwareMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
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Sample preparation for polar metabolites in bioanalysisDrouin, Nicolas; Rudaz, Serge; Schappler, Julie;
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Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss menZufferey, Fanny; Rahban, Rita; Garcia, Arnaud; Gagnebin, Yoric; ... Rossier, Michel F
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Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activityDiop, ElHadji Assane; Queiroz, Emerson Ferreira; Kicka, Sébastien; Rudaz, Serge; ... Wolfender, Jean-Luc

Thesis supervisions

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Blood biomarkers in acute brain injury disordersLagerstedt, Linnéa;
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Étude de plantes médicinales et contrôle de qualité des préparations utilisées dans le traitement de la tuberculose au SénégalDiop, El Hadji Assane;

2017

Scientific Articles

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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferasesRomand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge
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Development of a New Extraction Device Based on Parallel- Electromembrane ExtractionDrouin, Nicolas; Mandscheff, Jean François; Rudaz, Serge; Schappler, Julie;
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ERE-dependent transcription and cell proliferation: Independency of these two processes mediated by the introduction of a sulfone function into the weak estrogen estrothiazineJacquot, Yves; Spaggiari, Dany; Schappler, Julie; Lesniewska, Eric; ... Leclercq, Guy
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HDM-PAMPA to predict gastrointestinal absorption, binding percentage, equilibrium and kinetics constants with human serum albumin and using 2 end-point measurementsBujard, Alban; Petit, Charlotte; Carrupt, Pierre-Alain; Rudaz, Serge; Schappler, Julie
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Indirect quantitative structure-retention relationship for steroid identification: A chemometric challenge at "Chimiométrie 2016"Randazzo, Giuseppe Marco; Vigneau, Evelyne; Courcoux, Philippe; Harrouet, Corentin; ... Rudaz, Serge
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Long-term stability of ganciclovir in polypropylene containers at room temperatureGuichard, Nicolas; Bonnabry, Pascal; Rudaz, Serge; Fleury, Sandrine;
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Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategiesGagnebin, Yoric; Tonoli, David; Lescuyer, Pierre; Ponte, Belen; ... Rudaz, Serge
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Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugatesBobaly, Balazs; Randazzo, Giuseppe Marco; Rudaz, Serge; Guillarme, Davy; Fekete, Szabolcs
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Stability of busulfan solutions in polypropylene syringes and infusion bags as determined with an original assayGuichard, Nicolas; Bonnabry, Pascal; Rudaz, Serge; Fleury-Souverain, Sandrine;
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Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroidsStrajhar, Petra; Tonoli, David; Jeanneret, Fabienne; Imhof ., Raphaella M; ... Odermatt, Alex
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Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized MedicineMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;

Thesis supervisions

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Biomarkers for prediction of cerebrovascular diseases associated complications and outcomeAzurmendi Gil, Leire;
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CYP450-mediated drug-drug interactions: towards prediction and informed dose recommendation using physiologically-based pharmacokinetic (PBPK) modelingMarsousi, Niloufar;

2016

Scientific Articles

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An extensive cocktail approach for rapid risk assessment of in vitro CYP450 direct reversible inhibition by xenobiotic exposureSpaggiari, Dany; Daali, Youssef; Rudaz, Serge;
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Analysis of Riboflavin Compounds in the Rabbit Cornea In VivoHammer, Arthur; Rudaz, Serge; Guinchard, Sylvie; Kling, Sabine; ... Hafezi, Farhad
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Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approachMarsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef
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Dynamic-Electromembrane Extraction: A Technical Development for the Extraction of NeuropeptidesDrouin, Nicolas; Rudaz, Serge; Schappler, Julie;
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Evaluation and identification of dioxin exposure biomarkers in human urine by high-resolution metabolomics, multivariate analysis and in vitro synthesisJeanneret, Fabienne; Tonoli, David; Hochstrasser, Denis; Saurat, Jean-Hilaire; ... Rudaz, Serge
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Evaluation of a new low sheath–flow interface for CE-MSGonzalez Ruiz, Victor; Codesido Sanchez, Santiago; Far, Johann; Rudaz, Serge; Schappler, Julie
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Evaluation of Quantification Methods to Compensate for Matrix Effects in the Analysis of Benzalkonium Chloride and Didecyldimethylammonium Chloride in Fruits and Vegetables by LC-ESI-MS/MSDiez, Cristina; Feinberg, Max; Staub Sporri, Aline; Cognard, Emmanuel; ... Rudaz, Serge
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Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbationsJeanneret, Fabienne; Tonoli, David; Rossier, Michel; Saugy, Martial; ... Rudaz, Serge
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Exploring Omics data from designed experiments using analysis of variance multiblock Orthogonal Partial Least SquaresBoccard, Julien; Rudaz, Serge;
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High-throughput identification of monoclonal antibodies after compounding by UV spectroscopy coupled to chemometrics analysisJacoulet, Emmanuel; Boccard, Julien; Taverna, Myriam; Santos Azevedos, Andrea; ... Smadja, Claire
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Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cellsMarsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef
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Longitudinal monitoring of endogenous steroids in human serum by UHPLC-MS/MS as a tool to detect testosterone abuse in sportsPonzetto, Federico; Mehl, Florence; Boccard, Julien; Baume, Norbert; ... Nicoli, Raul
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Prediction of retention time in reversed-phase liquid chromatography as a tool for steroid identificationRandazzo, Giuseppe Marco; Tonoli, David; Hambye, Stéphanie; Guillarme, Davy; ... Rudaz, Serge
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Separation of substrates and closely related glucuronide metabolites using various chromatographic modesRomand, Stéphanie Anne; Rudaz, Serge; Guillarme, Davy;
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Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in MixturesBertrand, Samuel; Azzollini, Antonio; Nievergelt-Meier, Andreas; Boccard, Julien; ... Wolfender, Jean-Luc

Book Chapters

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Capillary Electrophoresis-Ultraviolet-Mass Spectrometry (CE-UV-MS) for the Simultaneous Determination and Quantification of Insulin FormulationsSchappler, Julie; Rudaz, Serge;
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CE-MS in Drug Analysis and BioanalysisSchappler, Julie; Gonzalez Ruiz, Victor; Rudaz, Serge;

Thesis supervisions

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Nouvelles approches in vitro pour l'étude de la physico-chimie et du métabolisme de phase II de composés pharmaceutiquesRomand, Stéphanie Anne;

2015

Scientific Articles

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Aminoglycoside analysis in food of animal origin with a zwitterionic stationary phase and liquid chromatography–tandem mass spectrometryDiez, Cristina; Guillarme, Davy; Staub Sporri, Aline; Cognard, Emmanuelle; ... Rudaz, Serge
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Efficacity of Two Cleaning Solutions for the Decontamination of 10 Antineoplastic Agents in the Biosafety Cabinets of a Hospital PharmacyAnastasi, Marco; Rudaz, Serge; Queruau Lamerie, Thomas; Odou, Pascal; ... Fleury, Sandrine
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Evaluation of chemical contamination of surfaces during the preparation of chemotherapies in 24 hospital pharmaciesFleury, Sandrine; Mattiuzzo, Marc; Mehl, Florence; Nussbaumer, Susanne; ... Bonnabry, Pascal
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Inhibition screening method of microsomal UGTs using the cocktail approachGradinaru, Julieta; Romand, Stéphanie Anne; Geiser, Laurent; Carrupt, Pierre-Alain; ... Rudaz, Serge
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Integrating metabolomic data from multiple analytical platforms for a comprehensive characterisation of lemon essential oilsMehl, Florence; Marti, Guillaume; Merle, Philippe; Delort, Estelle; ... Boccard, Julien
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Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High- Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R CellsTonoli, David; Furstenberger, Cornelia; Boccard, Julien; Hochstrasser, Denis; ... Rudaz, Serge
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Treatment with KLEPTOSE® CRYSMEB reduces mouse atherogenesis by impacting on lipid profile and Th1 lymphocyte responseMontecucco, Fabrizio; Lenglet, Sébastien; Carbone, Federico; Boero, Silvia; ... Mach, François

Thesis supervisions

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In vitro assessment of human hepatic cytochrome P450 activities using liquid chromatography-mass spectrometrySpaggiari, Dany;
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Studies of PAMPA permeability values and its application for protein - drug interaction determinationBujard, Alban;
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