Guillarme, Davy

 
 
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2018

Scientific Articles

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Adding a new separation dimension to MS and LC–MS: What is the utility of ion mobility spectrometry?D'Atri, Valentina; Causson, Tim; Hernandez-Alba, Oscar; Mutabazi, Aline; ... Guillarme, Davy
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An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug ConjugatesEhkirch, Antony; D'Atri, Valentina; Rouviere, Florent; Hernandez-Alba, Oscar; ... Cianferani, Sarah
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Applicability of supercritical fluid chromatography–mass spectrometry to metabolomics. I – Optimization of separation conditions for the simultaneous analysis of hydrophilic and lipophilic substancesDesfontaine, Vincent; Losacco, Gioacchino Luca; Gagnebin, Yoric; Pezzatti, Julian; ... Guillarme, Davy
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Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometryD'Atri, Valentina; Fekete, Szabolcs; Stoll, Dwight; Lauber, Matthew; ... Guillarme, Davy
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Current possibilities of liquid chromatography for the characterization of antibody-drug conjugatesBobaly, Balazs; Fleury, Sandrine; Beck, Alain; Veuthey, Jean-Luc; ... Fekete, Szabolcs
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Development of a lc–ms/ms method for the determination of isomeric glutamyl peptides in food ingredientsDesfontaine, Vincent; Goyon, Alexandre; Veuthey, Jean-Luc; Charve, Joséphine; Guillarme, Davy
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Development of Comprehensive Online Two-Dimensional Liquid Chromatography/Mass Spectrometry Using Hydrophilic Interaction and Reversed-Phase Separations for Rapid and Deep Profiling of Therapeutic AntibodiesStoll, Dwight R.; Harmes, David C.; Staples, Gregory O.; Potter, Oscar G.; ... Beck, Alain
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Extending the limits of size exclusion chromatography: Simultaneousseparation of free payloads and related species from antibody drugconjugates and their aggregatesGoyon, Alexandre; Sciascera, Luca; Clarke, Adrien; Guillarme, Davy; Pell, Reinhard
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Hyphenation of size exclusion chromatography to native ion mobility mass spectrometry for the analytical characterization of therapeutic antibodies and related productsEhkirch, Antony; Hernandez-Alba, Oscar; Colas, Olivier; Guillarme, Davy; Cianférani, Sarah
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Implementation of a generic liquid chromatographic methoddevelopment workflow: Application to the analysis ofphytocannabinoids and Cannabis sativa extractsFekete, Szabolcs; Sadat-Noorbakhsh, Vida; Schelling, Cédric; Molnar, Imre; ... Veuthey, Jean-Luc
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Improved separation by at-column dilution in preparative hydrophilicinteraction chromatographyJaffuel, Geoffrey; Chappuis, Laura; Guillarme, Davy; Turlings, Ted C.J.; Glauser, Gaétan
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Influence of connection tubing in modern size exclusionchromatography and its impact on the characterization of mAbsFekete, Szabolcs; Guillarme, Davy;
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Monoclonal antibody N-glycosylation profiling using capillary electrophoresis – Mass spectrometry: Assessment and method validationGiorgetti, Jérémie; D'Atri, Valentina; Canonge, Julie; Lechner, Antony; ... François, Yannis-Nicolas
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Natural compounds analysis using liquid and supercritical fluid chromatography hyphenated to mass spectrometry: Evaluation of a new design of atmospheric pressure ionization sourceCiclet, Olivier; Barron, Denis; Bajic, Steve; Veuthey, Jean-Luc; ... Grand-Guillaume-Perrenoud, Alexandre
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New developments and possibilities of wide-pore superficially porous particle technology applied for the liquid chromatographic analysis of therapeutic proteinsBobaly, Balazs; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs;
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Size Exclusion Chromatography of Protein Biopharmaceuticals: Past, Present and FutureFekete, Szabolcs; Goyon, Alexandre; Veuthey, Jean-Luc; Guillarme, Davy;
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Systematic evaluation of matrix effects in supercritical fluid chromatography versus liquid chromatography coupled to mass spectrometry for biological samplesDesfontaine, Vincent; Capetti, France4sca; Nicoli, Raul; Kuuranne, Tiia; ... Guillarme, Davy
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Unraveling the mysteries of modern size exclusion chromatography – the way to achieve confident characterization of therapeutic proteinsGoyon, Alexandre; Fekete, Szabolcs; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy
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Utility of a high coverage phenyl-bonding and wide-pore superficially porous particle for the analysis of monoclonal antibodies and relatedproductsBobaly, Balazs; Lauber, Matthew; Beck, Alain; Guillarme, Davy; Fekete, Szabolcs
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What are the current solutions for interfacing supercritical fluid chromatography and mass spectrometry?Guillarme, Davy; Desfontaine, Vincent; Heinisch, Sabine; Veuthey, Jean-Luc;

Thesis supervisions

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The use of modern supercritical fluid chromatography and supercritical fluid chromatography - mass spectrometry in pharmaceutical analysisDesfontaine, Vincent;

2017

Scientific Articles

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A systematic investigation of sample diluents in modern supercritical fluid chromatographyDesfontaine, Vincent; Tarafder, Abhijit; Hill, Jason; Fairchild, Jacob; ... Guillarme, Davy
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A workflow for column interchangeability in liquid chromatographyusing modeling software and quality-by-design principlesKormany, Robert; Tamas, Katalin; Guillarme, Davy; Fekete, Szabolcs;
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Achievable separation performance and analysis time in current liquid chromatographic practice for monoclonal antibody separationsFekete, Szabolcs; Veuthey, Jean-Luc; Guillarme, Davy;
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Alternative Strategies to Reversed-Phase Liquid Chromatography for the Analysis of Pharmaceutical CompoundsGuillarme, Davy; Veuthey, Jean-Luc;
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Analysis of recombinant monoclonal antibodies in hydrophilicinteraction chromatography: A generic method developmentapproachBobaly, Balazs; D'Atri, Valentina; Beck, Alain; Guillarme, Davy; Fekete, Szabolcs
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Analytical Characterization of BiopharmaceuticalsGuillarme, Davy;
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Antineoplastic drugs and their analysis: a state of the art reviewGuichard, Nicolas; Guillarme, Davy; Bonnabry, Pascal; Fleury-Souverain, Sandrine;
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Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenationGoyon, Alexandre; D'Atri, Valentina; Colas, Olivier; Fekete, Szabolcs; ... Guillarme, Davy
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Comprehensive study on the effects of sodium and potassiumadditives in size exclusion chromatographic separations of proteinbiopharmaceuticalsGoyon, Alexandre; Beck, Alain; Veuthey, Jean-Luc; Guillarme, Davy; Fekete, Szabolcs
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Computer-Assisted Method Development for Small and Large MoleculesFekete, Szabolcs; Kormàni, Robert; Guillarme, Davy;
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Development of a fast workflow to screen the charge variants of therapeutic antibodiesWagner-Rousset, Elsa; Fekete, Szabolcs; Morel-Chevillet, Laura; Colas, Olivier; ... Beck, Alain
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HPLC Teaching Assistant: A New Tool for Learning and Teaching Liquid Chromatography, Part 1Guillarme, Davy; Veuthey, Jean-Luc;
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Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugatesBobaly, Balazs; Randazzo, Giuseppe Marco; Rudaz, Serge; Guillarme, Davy; Fekete, Szabolcs
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Optimized selection of liquid chromatography conditions for widerange analysis of natural compoundsPeriat, Aurélie Claudine; Guillarme, Davy; Veuthey, Jean-Luc; Boccard, Julien; ... Grand-Guillaume Perrenoud, Alexandre
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. I - Non-denaturing chromatographic techniquesGoyon, Alexandre; D'Atri, Valentina; Bobaly, Balazs; Wagner-Rousset, Elsa; ... Guillarme, Davy
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Protocols for the analytical characterization of therapeutic monoclonal antibodies. II – Enzymatic and chemical sample preparationBobaly, Balazs; Goyon, Alexandre; D'Atri, Valentina; Colas, Olivier; ... Guillarme, Davy
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Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatographyDispas, Amandine; Desfontaine, Vincent; Andri, Bertyl; Lebrun, Pierre; ... Hubert, Philippe
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Separation of antibody drug conjugate species by RPLC: A genericmethod development approachFekete, Szabolcs; Molnar, Imre; Guillarme, Davy;
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The importance of system band broadening in modern size exclusion chromatographyGoyon, Alexandre; Guillarme, Davy; Fekete, Szabolcs;
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The key role of analytical sciences in the discovery and characterization of bioactives from food and nutraceuticalsGrand-Guillaume-Perrenoud, Alexandre; Allard, Pierre-Marrie; Ciclet, Oliver; Guillarme, Davy; ... Barron, Denis
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UHPLC, Part 2: BenefitsDong, Michael W.; Guillarme, Davy;
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UHPLC, Part II: BenefitsDong, Michael W.; Guillarme, Davy;

Book Chapters

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Hyphenated Detectors: Mass SpectrometryDesfontaine, Vincent; Veuthey, Jean-Luc; Guillarme, Davy;
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Theory and Practice of UHPLC and UHPLC-MSGuillarme, Davy; Veuthey, Jean-Luc;
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