Maechler, Pierre

 
 
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2017

Scientific Articles

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Bone Regulates Browning and Energy Metabolism Through Mature Osteoblast/Osteocyte PPARγ ExpressionBrun, Julia; Berthou, Flavien; Trajkovski, Mirko; Maechler, Pierre; ... Bonnet, Nicolas
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Chronic orexin-A (hypocretin-1) treatment of type 2 diabetic rats improves glucose control and beta-cell functionsKaczmarek, P; Skrzypski, M; Pruszynska-Oszmalek, E; Sassek, M; ... Strowski, M Z
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Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state?Pournourmohammadi, Shirin; Grimaldi, Mariagrazia; Stridh, Malin H; Lavallard, Vanessa; ... Maechler, Pierre
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Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulationHohnholt, Michaela C; Andersen, Vibe H; Andersen, Jens V; Christensen, Sofie K; ... Waagepetersen, Helle S
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Glutamate pathways of the beta-cell and the control of insulin secretionMaechler, Pierre;
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Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemiaGrimaldi, Mariagrazia; Karaca Emre, Melis; Latini, Livia; Brioudes, Estelle; ... Maechler, Pierre
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Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid ProductionDalmas, Elise; Lehmann, Frank M; Dror, Erez; Wueest, Stephan; ... Donath, Marc Y
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Upregulation of UCP2 in beta-cells confers partial protection against both oxidative stress and glucotoxicityLi, Ning; Karaca Emre, Melis; Maechler, Pierre;

Thesis supervisions

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Mitochondrial function and morphology in prohibitin 2 deleted ß-cells and hepatocytesLi, Lingzi;

2014

Scientific Articles

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A possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic isletsSileno, Sara; D'Oria, Valentina; Stucchi, Riccardo; Alessio, Massimo; ... Massa, Ornella

2011

Scientific Articles

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A role for pancreatic beta-cell secretory hyperresponsiveness in catch-up growth hyperinsulinemia: Relevance to thrifty catch-up fat phenotype and risks for type 2 diabetesCasimir, Marina Shamini; de Andrade, Paula B; Gjinovci, Asllan; Montani, Jean-Pierre; ... Dulloo, Abdul G
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ChREBP mediates glucose repression of peroxisome proliferator-activated receptor alpha expression in pancreatic beta-cellsBoergesen, Michael; Poulsen, Lars la Cour; Schmidt, Søren Fisker; Frigerio, Francesca; ... Mandrup, Susanne
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Effects of olive leaf polyphenols against H₂O₂ toxicity in insulin secreting β-cellsCumaoğlu, Ahmet; Rackova, Lucia; Stefek, Milan; Kartal, Murat; ... Karasu, Cimen
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From pancreatic islets to central nervous system, the importance of glutamate dehydrogenase for the control of energy homeostasisKaraca Emre, Melis; Frigerio, Francesca; Maechler, Pierre;
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Non-invasive imaging of ferucarbotran labeled INS-1E cells and rodent islets in vitro and in transplanted diabetic ratsAuer, Veronika J; Bucher, Julian; Schremmer-Danninger, Elisabeth; Paulmurugan, Ramasamy; ... Berger, Frank
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Novel hexahydropyridoindole derivative as prospective agent against oxidative damage in pancreatic β cellsRačková, Lucia; Cumaoğlu, Ahmet; Bağrıacık, E Umit; Štefek, Milan; ... Karasu, Çimen
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Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanismVetterli, Laurene Marine; Brun, Thierry; Giovannoni, Laurianne; Bosco, Domenico; Maechler, Pierre
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Resveratrol-activated SIRT1 in liver and pancreatic β-cells: a Janus head looking to the same direction of metabolic homeostasisVetterli, Laurene Marine; Maechler, Pierre;

Thesis supervisions

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Etude de la sensibilité au glucose et du couplage métabolisme-sécrétion dans les cellules d'insulinome INS-1E durant deux années de culture continueMerglen, Arnaud;
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Generation and characterization of an inducible conditional b-cell-specific glutamate dehydrogenase knockout mouseVetterli, Laurene Marine;
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