Maechler, Pierre

 
 
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2019

Scientific Articles

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Chronic fructose renders pancreatic beta-cells hyper-responsive to glucose-stimulated insulin secretion through extracellular ATP signalingBartley, Clarissa; Brun, Thierry; Oberhauser, Lucie; Grimaldi, Mariagrazia; ... Maechler, Pierre
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Glutamate Dehydrogenase-Deficient Mice Display Schizophrenia-Like Behavioral Abnormalities and CA1-Specific Hippocampal DysfunctionLander, Sharon S; Khan, Usman; Lewandowski, Nicole; Chakraborty, Darpan; ... Gaisler-Salomon, Inna
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In vivo stabilization of OPA1 in hepatocytes potentiates mitochondrial respiration and gluconeogenesis in a prohibitin-dependent wayLi, Lingzi; Martin-Levilain, Juliette; Jimenez-Sanchez, Cécilia; Karaca Emre, Melis; ... Maechler, Pierre
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Metabolomics identifies a biomarker revealing in vivo loss of functional ß-cell mass before diabetes onsetLi, Lingzi; Krznar, Petra; Erban, Alexander; Agazzi, Andréa; ... Maechler, Pierre
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Reply to Mishra: prohibitin heterodimers—a complex time dependence for carcinogenesisMartin-Levilain, Juliette; Li, Lingzi; Maechler, Pierre;
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Resveratrol long-term treatment differentiates INS-1E beta-cell towards improved glucose response and insulin secretionCasimir, Marina Shamini; Chaffard, Gaelle; Maechler, Pierre;

Professional Articles

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L’exposition des cellules bêta au fructose potentialise la sécrétion d’insuline via une signalisation par l’ATPBrun, Thierry; Bartley, Clarissa; Maechler, Pierre;

Thesis supervisions

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Characterization of KIAA2022 and generation of knock-out mice indicates a role in maintaining genomic stabilityStekelenburg, Caroline;
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Role Of FFAR1 in the response of INS-1E β-cells to glucolipotoxicityOberhauser, Lucie;

2017

Scientific Articles

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Bone Regulates Browning and Energy Metabolism Through Mature Osteoblast/Osteocyte PPARγ ExpressionBrun, Julia; Berthou, Flavien; Trajkovski, Mirko; Maechler, Pierre; ... Bonnet, Nicolas
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Chronic orexin-A (hypocretin-1) treatment of type 2 diabetic rats improves glucose control and beta-cell functionsKaczmarek, P; Skrzypski, M; Pruszynska-Oszmalek, E; Sassek, M; ... Strowski, M Z
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Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state?Pournourmohammadi, Shirin; Grimaldi, Mariagrazia; Stridh, Malin H; Lavallard, Vanessa; ... Maechler, Pierre
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Glutamate pathways of the beta-cell and the control of insulin secretionMaechler, Pierre;
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Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemiaGrimaldi, Mariagrazia; Karaca Emre, Melis; Latini, Livia; Brioudes, Estelle; ... Maechler, Pierre
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Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid ProductionDalmas, Elise; Lehmann, Frank M; Dror, Erez; Wueest, Stephan; ... Donath, Marc Y
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Upregulation of UCP2 in beta-cells confers partial protection against both oxidative stress and glucotoxicityLi, Ning; Karaca Emre, Melis; Maechler, Pierre;

Thesis supervisions

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Mitochondrial function and morphology in prohibitin 2 deleted ß-cells and hepatocytesLi, Lingzi;

2014

Scientific Articles

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A possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic isletsSileno, Sara; D'Oria, Valentina; Stucchi, Riccardo; Alessio, Massimo; ... Massa, Ornella
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