Highlights
Wang, Haiyan
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2012
Scientific Articles
 | Human Krüppel-like factor 11 differentially regulates human insulin promoter activity in β-cells and non-β-cells via p300 and PDX1 through the regulatory sites A3 and CACCC box | Perakakis, Nikolaos; Danassi, Despoina; Alt, Marcus; Tsaroucha, Eleni; ... Päth, Günter |
2011
Scientific Articles
| Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass | Esterházy, Daria; Stützer, Ina; Wang, Haiyan; Rechsteiner, Markus P; ... Stoffel, Markus |
| Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress | Kirkpatrick, Clare; Wiederkehr, Andreas; Baquie, Mathurin; Akhmedov, Dmitry; ... Wollheim, Claes |
| Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo | Uhles, S; Wang, Haiyan; Bénardeau, A; Prummer, M; ... Sebokova, E |
| The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis | Baquie, Mathurin; St-Onge, Luc; Kerr-Conte, Julie; Cobo-Vuilleumier, Nadia; ... Gauthier, Benoît |
2010
Scientific Articles
| Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation | Wallin, Tina; Ma, Zuheng; Ogata, Hirotaka; Jørgensen, Ingrid Hals; ... Björklund, Anneli |
2009
Scientific Articles
| Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis | Men, Xiuli; Wang, Haiyan; Li, Mi; Cai, Hanqing; ... Lou, Jinning |
2008
Scientific Articles
| The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cells | Perilhou, Anaïs; Tourrel-Cuzin, Cécile; Zhang, Pili; Kharroubi, Ilham; ... Vasseur-Cognet, Mireille |
| TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosis | Qian, Bo; Wang, Haiyan; Men, Xiuli; Zhang, Wenjian; ... Lou, Jinning |
2007
Scientific Articles
| Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy | Keller, David M; McWeeney, Shannon; Arsenlis, Athanasios; Drouin, Jacques; ... Goodman, Richard H |
| Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets | Bergholdt, R; Karlsen, A E; Hagedorn, P H; Aalund, M; ... Pociot, F |
2005
Scientific Articles
| Does chasing selected 'Fox' to the nucleus prevent diabetes? | Wang, Haiyan; Wollheim, Claes; |
| Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells | Wang, Haiyan; Iezzi, M.; Theander, Sten; Antinozzi, P. A.; ... Wollheim, Claes |
| The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation | Fukui, Kenji; Yang, Qin; Cao, Yang; Takahashi, Noriko; ... Yamagata, Kazuya |
2004
Scientific Articles
| Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity | Nielsen, K; Kruhøffer, M; Orntoft, T; Sparre, T; ... Karlsen, A E |
2002
Scientific Articles
| Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death | Wobser, Hella; Düssmann, Heiko; Kögel, Donat; Wang, Haiyan; ... Prehn, Jochen H M |
| Experimental models of transcription factor-associated maturity-onset diabetes of the young | Wang, Haiyan; Hagenfeldt-Johansson, Kerstin; Otten, L. A.; Gauthier, B. R.; ... Wollheim, Claes |
| Foxa2 (HNF3beta) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release | Wang, Haiyan; Gauthier, Benoît; Hagenfeldt-Johansson, Kerstin Arlette; Iezzi-Bakhtiari, Mariella; Wollheim, Claes |
2001
Scientific Articles
2000
Scientific Articles
1999
Scientific Articles
1998
Scientific Articles
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