Nef, Serge

 
 
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2019

Scientific Articles

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Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and MiceCoutton, Charles; Martinez, Guillaume; Kherraf, Zine-Eddine; Amiri-Yekta, Amir; ... Ray, Pierre F
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Characterizing the bipotential mammalian gonadNef, Serge; Stevant, Isabelle; Greenfield, Andy;
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Dissecting Cell Lineage Specification and Sex Fate Determination in Gonadal Somatic Cells Using Single-Cell TranscriptomicsStevant, Isabelle; Kuhne, Françoise; Greenfield, Andy; Chaboissier, Marie-Christine; ... Nef, Serge
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Genetic Control of Gonadal Sex Determination and DevelopmentStevant, Isabelle; Nef, Serge;
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Genetic resistance to DEHP-induced transgenerational endocrine disruptionStenz, Ludwig; Rahban, Rita; Prados, Julien; Nef, Serge; Giacobino, Ariane
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Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndromeMcElreavey, Ken; Jorgensen, Anne; Eozenou, Caroline; Merel, Tiphanie; ... Bashamboo, Anu
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Semen quality of young men in Switzerland: a nationwide cross‐sectional population‐based studyRahban, Rita; Priskorn, L.; Senn, Alfred Paul; Stettler, Eric; ... Nef, Serge
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The insulin/IGF system in mammalian sexual development and reproductionNeirijnck, Yasmine; Papaioannou, Maria-Eleni; Nef, Serge;
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The ReproGenomics Viewer: a multi-omics and cross-species resource compatible with single-cell studies for the reproductive science communityDarde, Thomas A; Lecluze, Estelle; Lardenois, Aurélie; Stevant, Isabelle; ... Chalmel, Frédéric
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Tumor Suppressor PTEN Regulates Negatively Sertoli Cell Proliferation, Testis Size, and Sperm Production In VivoNeirijnck, Yasmine; Kuhne, Françoise; Mayere, Chloé; Pavlova, Ekaterina; ... Nef, Serge

Thesis supervisions

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A nation-wide cross-sectional study on semen quality of young Swiss men and the effects of antidepressant drugs on human spermRahban, Rita;

2018

Scientific Articles

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A brief history of sex determinationStevant, Isabelle; Papaioannou, Marilena D; Nef, Serge;
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A Case of Two Sisters Suffering from 46,XY Gonadal Dysgenesis and Carrying a Mutation of a Novel Candidate Sex-Determining Gene STARD8 on the X ChromosomeIlaslan, Erkut; Calvel, Pierre; Nowak, Dominika; Szarras-Czapnik, Maria; ... Kusz-Zamelczyk, Kamila
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Creation of knock out and knock in mice by CRISPR/Cas9 to validate candidate genes for human male infertility, interest, difficulties and feasibilityKherraf, Zine-Eddine; Conne, Béatrice; Amiri-Yekta, Amir; Kent, Marie Christou; ... Ray, Pierre F
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Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA SequencingStevant, Isabelle; Neirijnck, Yasmine; Borel, Christelle; Escoffier Breancon, Jessica; ... Nef, Serge
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Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cellsNeirijnck, Yasmine; Calvel, Pierre; Kilcoyne, Karen R; Kuhne, Françoise; ... Nef, Serge
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Insulin/IGF1 signalling regulates the mitochondrial biogenesis markers in steroidogenic cells of prepubertal testis, but not ovaryRadovic, Sava M; Starovlah, Isidora M; Cap, Ivan; Miljkovic, Dejan; ... Andric, Silvana A
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Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and humanCoutton, Charles; Conne, Béatrice; Escoffier Breancon, Jessica; Nef, Serge;
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NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testisGregoire, Elodie P; Stevant, Isabelle; Chassot, Anne-Amandine; Martin, Luc; ... Chaboissier, Marie-Christine
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PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and miceChristou-Kent, Marie; Kherraf, Zine-Eddine; Amiri-Yekta, Amir; Le Blévec, Emilie; ... Arnoult, Christophe
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Single cell transcriptome sequencing: A new approach for the study of mammalian sex determinationStevant, Isabelle; Nef, Serge;
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Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss menZufferey, Fanny; Rahban, Rita; Garcia, Arnaud; Gagnebin, Yoric; ... Rossier, Michel F
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The impact of new technologies in our understanding of testis formation and functionNef, Serge; Wilhelm, Dagmar;
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ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signalingHarris, Abigail; Siggers, Pam; Corrochano, Silvia; Warr, Nick; ... Greenfield, Andy

Thesis supervisions

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Monitoring gonadal somatic cell differentiation during sex determination using single-cell RNA sequencingStevant, Isabelle;
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