2016

Scientific Articles

unige:88663	A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris	Cerini, Fabrice; Gaertner, Hubert François; Madden, Knut; Tolstorukov, Ilya; ... Hartley, Oliver
unige:88664	Association between anti-apolipoprotein A-1 antibodies and cardiovascular disease in the general population. Results from the CoLaus study	Antiochos, Panagiotis; Marques-Vidal, Pedro; Virzi, Julien; Pagano, Sabrina; ... Vuilleumier, Nicolas
unige:88575	Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants	Belnoue, Elodie; Di Berardino-Besson, Wilma; Gaertner, Hubert François; Carboni, Susanna; ... Derouazi, Madiha
unige:88614	Generating Chemokine Analogs with Enhanced Pharmacological Properties Using Phage Display	Dorgham, Karim; Cerini, Fabrice; Gaertner, Hubert François; Melotti, Astrid; ... Hartley, Oliver
unige:99154	Recombinant Antibodies for Academia: A Practical Approach	Cosson, Pierre; Hartley, Oliver;

2015

Scientific Articles

unige:73898	CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells	Fox, James M; Kasprowicz, Richard; Hartley, Oliver; Signoret, Nathalie;
unige:73895	Potent Anti-HIV Chemokine Analogs Direct Post-Endocytic Sorting of CCR5	Boensch, Claudia; Munteanu, Nicoleta Mihaela; Rossitto-Borlat, Irène; Fuerstenberg, Alexandre; Hartley, Oliver
unige:81134	The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease?	Pagano, Sabrina; Gaertner, Hubert François; Cerini, Fabrice; Mannic, Tiphaine; ... Hartley, Oliver

Thesis supervisions

unige:74935

Dissecting the mechanism of action of an anti-TLR4 antibody

Loyau, Jeremy;

2014

Scientific Articles

unige:73893	Autoantibodies to apolipoprotein A-1 as a biomarker of cardiovascular autoimmunity	Vuilleumier, Nicolas; Montecucco, Fabrizio; Hartley, Oliver;
unige:77876	Coordinate-based co-localization-mediated analysis of arrestin clustering upon stimulation of the C-C chemokine receptor 5 with RANTES/CCL5 analogues	Tarancon Diez, Laura; Boensch, Claudia; Malkusch, Sebastian; Truan, Zinnia; ... Fuerstenberg, Alexandre
unige:55615	Definition of human apolipoprotein A-I epitopes recognized by autoantibodies present in patients with cardiovascular diseases	Teixeira, Priscila Camillo; Ducret, Axel; Ferber, Philippe; Gaertner, Hubert François; ... Cutler, Paul
unige:73891	Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry	Jin, Jun; Colin, Philippe; Staropoli, Isabelle; Lima-Fernandes, Evelyne; ... Brelot, Anne
unige:73894	δ-Conotoxins synthesized using an acid-cleavable solubility tag approach reveal key structural determinants for NaV subtype selectivity	Peigneur, Steve; Paolini-Bertrand, Marianne; Gaertner, Hubert François; Biass, Daniel; ... Hartley, Oliver

2013

Scientific Articles

unige:43127	Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest	Kavanagh, J N; Currell, F J; Timson, D J; Savage, K I; ... Schettino, G
unige:42978	Characterization of structure, dynamics, and detergent interactions of the anti-HIV chemokine variant 5P12-RANTES.	Wiktor, Maciej; Hartley, Oliver; Grzesiek, Stephan;
unige:43126	HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines	Colin, Philippe; Bénureau, Yann; Staropoli, Isabelle; Wang, Yongjin; ... Lagane, Bernard
unige:43128	Identification, structural and pharmacological characterization of τ-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor	Petrel, C; Hocking, H G; Reynaud, M; Upert, G; ... Servent, D
unige:43123	Quantitative morphological analysis of arrestin2 clustering upon G protein-coupled receptor stimulation by super-resolution microscopy	Truan, Zinnia; Tarancon Diez, Laura; Boensch, Claudia; Malkusch, Sebastian; ... Fuerstenberg, Alexandre
unige:43124	Using glycosaminoglycan/chemokine interactions for the long-term delivery of 5P12-RANTES in HIV prevention	Wang, Nick X; Sieg, Scott F; Lederman, Michael M; Offord, Robin Ewart; ... von Recum, Horst A

2012

Scientific Articles

unige:23511	A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors	Favreau, Philippe; Benoit, Evelyne; Hocking, Henry G; Carlier, Ludovic; ... Molgó, Jordi
unige:23656	Alteration of synaptic network dynamics by the intellectual disability protein PAK3	Dubos, Aline; Combeau, Gaelle; Bernardinelli, Yann; Barnier, Jean-Vianney; ... Muller, Dominique
unige:23658	CCR5 Mutations Distinguish N-Terminal Modifications of RANTES (CCL5) with Agonist versus Antagonist Activity	Choi, Won-Tak; Nedellec, Rebecca; Coetzer, Mia; Colin, Philippe; ... Mosier, Donald E
unige:23657	Mechanism and molecular basis for the sodium channel subtype specificity of µ-conopeptide CnIIIC.	Markgraf, René; Leipold, Enrico; Schirmeyer, Jana; Paolini-Bertrand, Marianne; ... Heinemann, Stefan H
unige:23659	Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots	Shulman, Ziv; Cohen, Shmuel J; Roediger, Ben; Kalchenko, Vyacheslav; ... Alon, Ronen

2011

Scientific Articles

unige:23473	Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5	Pilch-Cooper, Heather A; Sieg, Scott F; Hope, Thomas J; Koons, Ann; ... Lederman, Michael M
unige:23480	Efficient orthogonal bioconjugation of dendrimers for synthesis of bioactive nanoparticles	Gaertner, Hubert François; Cerini, Fabrice; Kamath, Arun; Rochat, Anne-Françoise; ... Hartley, Oliver
unige:23510	Resistance to the CCR5 inhibitor 5P12-RANTES requires a difficult evolution from CCR5 to CXCR4 coreceptor use	Nedellec, Rebecca; Coetzer, Mia; Lederman, Michael M; Offord, Robin Ewart; ... Mosier, Donald E

2010

Scientific Articles

unige:21173	"Resistance" to PSC-RANTES revisited: two mutations in human immunodeficiency virus type 1 HIV-1 SF162 or simian-human immunodeficiency virus SHIV SF162-p3 do not confer resistance	Nedellec, Rebecca; Coetzer, Mia; Lederman, Michael M.; Offord, Robin Ewart; ... Mosier, Donald E.
unige:20927	CC chemokine receptor 5 (CCR5) desensitization: cycling receptors accumulate in the trans-Golgi network	Escola, Jean-Michel; Kuenzi, Gabriel; Gaertner, Hubert; Foti, Michelangelo; Hartley, Oliver
unige:20660	Deciphering the code for retroviral integration target site selection	Santoni, Federico; Hartley, Oliver; Luban, Jeremy;

2009

Scientific Articles

unige:19779	An engineered CX3CR1 antagonist endowed with anti-inflammatory activity	Dorgham, Karim; Ghadiri, Ata; Hermand, Patricia; Rodero, Mathieu; ... Deterre, Philippe
unige:20148	Topically applied recombinant chemokine analogues fully protect macaques from vaginal simian-human immunodeficiency virus challenge	Veazey, Ronald S.; Ling, Binhua; Green, Linda C.; Ribka, Erin P.; ... Hartley, Oliver
unige:19896	V-79 Chinese hamster cells irradiated with antiprotons, a study of peripheral damage due to medium and long range components of the annihilation radiation	Kovacevic, Sandra; Bassler, Niels; Hartley, Oliver; Knudsen, Helge; ... Holzscheiter, Michael

Thesis supervisions

unige:2065

Activation of the erythropoietin receptor by multivalent molecules

Vadas, Oscar Laurent;

2008

Scientific Articles

unige:2085	Antiproton radiotherapy	Bassler, Niels; Alsner, Jan; Beyer, Gerd; DeMarco, John J.; ... Holzscheiter, Michael H.
unige:873	Characterization of new multimeric erythropoietin receptor agonists	Vadas, Oscar Laurent; Hartley, Oliver; Rose, Keith;
unige:19120	Chemokine analogues show suitable stability for development as microbicides	Cerini, Fabrice; Landay, Alan; Gichinga, Carolyne; Lederman, Michael M.; ... Hartley, Oliver
unige:2086	Engineered CCR5 superagonist chemokine as adjuvant in anti-tumor DNA vaccination	Dorgham, Karim; Abadie, Valérie; Iga, Mutsunori; Hartley, Oliver; ... Combadière, Behazine
unige:815	Highly potent HIV inhibition: engineering a key anti-HIV structure from PSC-RANTES into MIP-1 beta/CCL4	Gaertner, Hubert Francois; Lebeau, Olivier; Borlat, Irène; Cerini, Fabrice; ... Hartley, Oliver
unige:1265	Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide	Gaertner, Hubert François; Cerini, Fabrice; Escola, Jean-Michel; Kuenzi, Gabriel; ... Hartley, Oliver
unige:670	Semisynthetic analogues of PSC-RANTES, a potent anti-HIV protein	Gaertner, Hubert Francois; Offord, Robin Ewart; Botti, Paolo; Kuenzi, Gabriel; Hartley, Oliver
unige:2087	Targeting chemokine receptors in HIV: a status report	Kuhmann, Shawn E.; Hartley, Oliver;

2007

Scientific Articles

unige:26022	Analysis of HIV-1-X4 fusion with immature dendritic cells identifies a specific restriction that is independent of CXCR4 levels	Pion, Marjorie; Arrighi, Jean-François; Jiang, Jiyang; Lundquist, Christopher A; ... Piguet, Vincent
unige:26020	C34, a membrane fusion inhibitor, blocks HIV infection of langerhans cells and viral transmission to T cells	Sugaya, Makoto; Hartley, Oliver; Root, Michael J; Blauvelt, Andrew;
unige:26023	Conserved changes in envelope function during human immunodeficiency virus type 1 coreceptor switching	Pastore, Cristina; Nedellec, Rebecca; Ramos, Alejandra; Hartley, Oliver; ... Mosier, Donald E
unige:11583	NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation	Serrander, Lena; Jaquet, Vincent; Bedard, Karen; Plastre, Olivier; ... Krause, Karl-Heinz

2006

Scientific Articles

unige:26028	HIV-1 coreceptor selectivity: structural analogy between HIV-1 V3 regions and chemokine beta-hairpins is not the explanation	Scheib, Holger; Sperisen, Peter; Hartley, Oliver;
unige:26026	Identification of peptide ligands to the chemokine receptor CCR5 and their maturation by gene shuffling	Vyroubalova, Eva Cachin; Hartley, Oliver; Mermod, Nicolas; Fisch, Igor;
unige:26031	Microbicides and other topical strategies to prevent vaginal transmission of HIV.	Lederman, Michael M; Offord, Robin Ewart; Hartley, Oliver;