2020

Scientific Articles

unige:144927	Arrestin recruitment to c-c chemokine receptor 5: potent c-c chemokine ligand 5 analogs reveal differences in dependence on receptor phosphorylation and isoform-specific recruitment bias	Martins, Elsa; Brodier, Hellena; Rossitto-Borlat, Irène; Cadosch, Ilke; ... Hartley, Oliver
unige:144926	CCR5 tyrosine sulfation heterogeneity generates cell surface receptor subpopulations with different ligand binding properties	Scurci, Ilaria; Akondi, Kalyana Bharati; De Magalhaes Pinheiro, Inês; Paolini-Bertrand, Marianne; ... Hartley, Oliver
unige:142447	Étudier la médecine humaine à l’Université de Genève: Un programme d’études intégré et innovant	Nendaz, Mathieu; Hartley, Oliver; Chanson, Marc; Savoldelli, Georges Louis;
unige:138770	RB110 and RB157 antibodies recognize by ELISA specific phosphorylation patterns on CCR5 C-terminal peptides	Paolini-Bertrand, Marianne; Rossitto-Borlat, Irène; Martins, Elsa; Hartley, Oliver;

Thesis supervisions

unige:139677

Use of chemokines and chemokine analogs to study intracellular C-terminal phosphorylation and arrestin recruitment to CCR5

Martins, Elsa;

2019

Scientific Articles

unige:122543	Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice	Steinbach, Karin; Vincenti, Ilena; Egervari, Kristof Levente; Kreutzfeldt, Mario; ... Merkler, Doron
unige:144928	Development and pharmacokinetics of a combination vaginal ring for sustained release of dapivirine and the protein microbicide 5P12-RANTES.	McBride, John W; Malcolm, R Karl; Dias, Nicola; Cameron, David; ... Boyd, Peter
unige:145009	High-affinity binding of chemokine analogs that display ligand bias at the HIV-1 coreceptor CCR5	Rico, Carlos A; Berchiche, Yamina A; Horioka, Mizuho; Peeler, Jennifer C; ... Huber, Thomas
unige:144925	IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration	Yshii, Lidia; Pignolet, Béatrice; Mauré, Emilie; Pierau, Mandy; ... Liblau, Roland
unige:144929	Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES.	McBride, John W; Boyd, Peter; Dias, Nicola; Cameron, David; ... Malcolm, R Karl

Thesis supervisions

unige:151394

The role of sulfation in CCR5 heterogeneity and its impact on chemokine and antibody binding

Scurci, Ilaria;

2018

Scientific Articles

unige:115874	CCR5: Established paradigms and new frontiers for a 'celebrity' chemokine receptor	Scurci, Ilaria; Martins, Elsa; Hartley, Oliver;
unige:115326	Preventing HIV transmission through blockade of CCR5: rationale, progress and perspectives	Martins, Elsa; Scurci, Ilaria; Hartley, Oliver;
unige:115805	Rapid and low-cost multiplex synthesis of chemokine analogs	Paolini-Bertrand, Marianne; Cerini, Fabrice; Martins, Elsa; Scurci, Ilaria; Hartley, Oliver
unige:110464	RB250 and RB251 antibodies recognize the human MitoNEET/CISD1 protein by ELISA	Hammel, Philippe; Lima, Wanessa Cristina; Hartley, Oliver; Cosson, Pierre;

2017

Scientific Articles

unige:108827	Anti-Apolipoprotein A-1 IgG Predict All-Cause Mortality and Are Associated with Fc Receptor-Like 3 Polymorphisms	Antiochos, Panagiotis; Marques-Vidal, Pedro; Virzi, Julien; Pagano, Sabrina; ... Vuilleumier, Nicolas
unige:112660	Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1	Yuzugulen, Jale; Douthwaite, Julie A; Wood, Elizabeth G; Villar, Inmaculada C; ... Corder, Roger
unige:112661	Dual display: phage selection driven by co-engagement of two targets by two different antibody fragments	Fagete, Séverine; Botas Perez, Ledicia; Rossitto-Borlat, Irène; Adea, Kenneth; ... Hartley, Oliver
unige:108546	Impact of CD14 Polymorphisms on Anti-Apolipoprotein A-1 IgG-Related Coronary Artery Disease Prediction in the General Population	Antiochos, Panagiotis; Marques-Vidal, Pedro; Virzi, Julien; Pagano, Sabrina; ... Vuilleumier, Nicolas
unige:112659	Pharmacokinetics of the Protein Microbicide 5P12-RANTES in Sheep following Single-Dose Vaginal Gel Administration	McBride, John W; Dias, Nicola; Cameron, David; Offord, Robin Ewart; ... Malcolm, R Karl
unige:112662	Stability of 5P12-RANTES, A Candidate Rectal Microbicide, in Human Rectal Lavage	Cerini, Fabrice; Offord, Robin Ewart; McGowan, Ian; Hartley, Oliver;

2016

Scientific Articles

unige:88663	A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris	Cerini, Fabrice; Gaertner, Hubert François; Madden, Knut; Tolstorukov, Ilya; ... Hartley, Oliver
unige:88664	Association between anti-apolipoprotein A-1 antibodies and cardiovascular disease in the general population. Results from the CoLaus study	Antiochos, Panagiotis; Marques-Vidal, Pedro; Virzi, Julien; Pagano, Sabrina; ... Vuilleumier, Nicolas
unige:88575	Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants	Belnoue, Elodie; Di Berardino-Besson, Wilma; Gaertner, Hubert François; Carboni, Susanna; ... Derouazi, Madiha
unige:88614	Generating Chemokine Analogs with Enhanced Pharmacological Properties Using Phage Display	Dorgham, Karim; Cerini, Fabrice; Gaertner, Hubert François; Melotti, Astrid; ... Hartley, Oliver
unige:99154	Recombinant Antibodies for Academia: A Practical Approach	Cosson, Pierre; Hartley, Oliver;

2015

Scientific Articles

unige:73898	CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells	Fox, James M; Kasprowicz, Richard; Hartley, Oliver; Signoret, Nathalie;
unige:73895	Potent Anti-HIV Chemokine Analogs Direct Post-Endocytic Sorting of CCR5	Boensch, Claudia; Munteanu, Nicoleta Mihaela; Rossitto-Borlat, Irène; Fuerstenberg, Alexandre; Hartley, Oliver
unige:81134	The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease?	Pagano, Sabrina; Gaertner, Hubert François; Cerini, Fabrice; Mannic, Tiphaine; ... Hartley, Oliver

Thesis supervisions

unige:74935

Dissecting the mechanism of action of an anti-TLR4 antibody

Loyau, Jeremy;

2014

Scientific Articles

unige:73893	Autoantibodies to apolipoprotein A-1 as a biomarker of cardiovascular autoimmunity	Vuilleumier, Nicolas; Montecucco, Fabrizio; Hartley, Oliver;
unige:77876	Coordinate-based co-localization-mediated analysis of arrestin clustering upon stimulation of the C-C chemokine receptor 5 with RANTES/CCL5 analogues	Tarancon Diez, Laura; Boensch, Claudia; Malkusch, Sebastian; Truan, Zinnia; ... Fuerstenberg, Alexandre
unige:55615	Definition of human apolipoprotein A-I epitopes recognized by autoantibodies present in patients with cardiovascular diseases	Teixeira, Priscila Camillo; Ducret, Axel; Ferber, Philippe; Gaertner, Hubert François; ... Cutler, Paul
unige:73891	Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry	Jin, Jun; Colin, Philippe; Staropoli, Isabelle; Lima-Fernandes, Evelyne; ... Brelot, Anne
unige:73894	δ-Conotoxins synthesized using an acid-cleavable solubility tag approach reveal key structural determinants for NaV subtype selectivity	Peigneur, Steve; Paolini-Bertrand, Marianne; Gaertner, Hubert François; Biass, Daniel; ... Hartley, Oliver

2013

Scientific Articles

unige:43127	Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest	Kavanagh, J N; Currell, F J; Timson, D J; Savage, K I; ... Schettino, G
unige:42978	Characterization of structure, dynamics, and detergent interactions of the anti-HIV chemokine variant 5P12-RANTES.	Wiktor, Maciej; Hartley, Oliver; Grzesiek, Stephan;
unige:43126	HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines	Colin, Philippe; Bénureau, Yann; Staropoli, Isabelle; Wang, Yongjin; ... Lagane, Bernard
unige:43128	Identification, structural and pharmacological characterization of τ-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor	Petrel, C; Hocking, H G; Reynaud, M; Upert, G; ... Servent, D
unige:43123	Quantitative morphological analysis of arrestin2 clustering upon G protein-coupled receptor stimulation by super-resolution microscopy	Truan, Zinnia; Tarancon Diez, Laura; Boensch, Claudia; Malkusch, Sebastian; ... Fuerstenberg, Alexandre
unige:43124	Using glycosaminoglycan/chemokine interactions for the long-term delivery of 5P12-RANTES in HIV prevention	Wang, Nick X; Sieg, Scott F; Lederman, Michael M; Offord, Robin Ewart; ... von Recum, Horst A

2012

Scientific Articles

unige:23511	A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors	Favreau, Philippe; Benoit, Evelyne; Hocking, Henry G; Carlier, Ludovic; ... Molgó, Jordi
unige:23656	Alteration of synaptic network dynamics by the intellectual disability protein PAK3	Dubos, Aline; Combeau, Gaelle; Bernardinelli, Yann; Barnier, Jean-Vianney; ... Muller, Dominique
unige:23658	CCR5 Mutations Distinguish N-Terminal Modifications of RANTES (CCL5) with Agonist versus Antagonist Activity	Choi, Won-Tak; Nedellec, Rebecca; Coetzer, Mia; Colin, Philippe; ... Mosier, Donald E
unige:23657	Mechanism and molecular basis for the sodium channel subtype specificity of µ-conopeptide CnIIIC.	Markgraf, René; Leipold, Enrico; Schirmeyer, Jana; Paolini-Bertrand, Marianne; ... Heinemann, Stefan H
unige:23659	Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots	Shulman, Ziv; Cohen, Shmuel J; Roediger, Ben; Kalchenko, Vyacheslav; ... Alon, Ronen

2011

Scientific Articles

unige:23473	Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5	Pilch-Cooper, Heather A; Sieg, Scott F; Hope, Thomas J; Koons, Ann; ... Lederman, Michael M
unige:23480	Efficient orthogonal bioconjugation of dendrimers for synthesis of bioactive nanoparticles	Gaertner, Hubert François; Cerini, Fabrice; Kamath, Arun; Rochat, Anne-Françoise; ... Hartley, Oliver
unige:23510	Resistance to the CCR5 inhibitor 5P12-RANTES requires a difficult evolution from CCR5 to CXCR4 coreceptor use	Nedellec, Rebecca; Coetzer, Mia; Lederman, Michael M; Offord, Robin Ewart; ... Mosier, Donald E

2010

Scientific Articles

unige:21173

"Resistance" to PSC-RANTES revisited: two mutations in human immunodeficiency virus type 1 HIV-1 SF162 or simian-human immunodeficiency virus SHIV SF162-p3 do not confer resistance

Nedellec, Rebecca; Coetzer, Mia; Lederman, Michael M.; Offord, Robin Ewart; ... Mosier, Donald E.