Desmeules, Jules Alexandre

 
 
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2020

Scientific Articles

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Cannabinoids and COVID-19El Biali, Myriam; Broers, Barbara; Besson, Marie; Desmeules, Jules Alexandre;
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Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in ChildrenDilo, Ana; Daali, Youssef; Desmeules, Jules Alexandre; Chalandon, Yves; ... Ansari Djaberi, Marc Georges
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Deep proteomics and phosphoproteomics reveal novel biological pathways perturbed by morphine, morphine-3-glucuronide and morphine-6-glucuronide in human astrocytesDozio, Vito; Daali, Youssef; Desmeules, Jules Alexandre; Sanchez, Jean-Charles;
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Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective StudyRollason, Victoria; Lloret-linaret, Célia; Ing Lorenzini, Kuntheavy; Daali, Youssef; ... Desmeules, Jules Alexandre
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GABAergic modulation of secondary hyperalgesia: A randomized controlled 4-way crossover trial with the α2-subunit preferring GABA positive allosteric modulator, N-desmethyl-clobazam in healthy volunteersMatthey, Alain; Daali, Youssef; Curtin, François; Poncet, Antoine; ... Besson, Marie
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Gender Differences in Cardiovascular Pharmacotherapy-the Example of Hypertension: A Mini ReviewKalibala, Jacklean; Pechere, Antoinette; Desmeules, Jules Alexandre;
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Impact of acute inflammation on cytochromes P450 activity assessed by the Geneva CocktailLenoir, Camille; Daali, Youssef; Rollason, Victoria; Curtin, François; ... Samer, Caroline Flora
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Outcomes of drug exposition during pregnancy: Analysis from a teratology information serviceLenoir, Camille; Boumaiza, Sabrina; Ing Lorenzini, Kuntheavy; Boulvain, Michel; ... Rollason, Victoria
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Pain interventions in adults with intellectual disability: A scoping review and pharmacological considerationsLonchampt, Sophie; Gerber, Fabienne; Aubry, Jean-Michel; Desmeules, Jules Alexandre; ... Besson, Marie
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Safety of the Geneva Cocktail, a Cytochrome P450 and P-Glycoprotein Phenotyping Cocktail, in Healthy Volunteers from Three Different Geographic OriginsRollason, Victoria; Mouterde, Médéric; Daali, Youssef; Čížková, Martina; ... Desmeules, Jules Alexandre
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Single center observational study on the role of demoralization and meaning in life in influencing suicidal ideation among patients affected by chronic pain (DEMiL study): A study protocolCostanza, Alessandra; Chytas, Vasileios; Mazzola, Viridiana; Piguet, Valérie; ... Cedraschi, Christine
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TOP-ID: a Delphi technique-guided development of a prescription and deprescription tool for adults with intellectual disabilitiesLonchampt, Sophie; Gerber, Fabienne Maria Y.; Aubry, Jean-Michel; Desmeules, Jules Alexandre; ... Kosel, Markus Mathaus

Professional Articles

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Opioïdes chez les patients âgés: Faux-amis ?El Biali, Myriam; Desmeules, Jules Alexandre; Besson, Marie;

2019

Scientific Articles

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A case report of cholinergic rebound syndrome following abrupt low-dose clozapine discontinuation in a patient with type I bipolar affective disorderGalova, Andréa; Berney, Patricia Elisabeth; Desmeules, Jules Alexandre; Sergentanis, Ioannis; Besson, Marie
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Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxinsSamer, Caroline Flora; Gloor, Yvonne Sylvia; Rollason Gumprecht, Victoria; Guessous, Idris; ... Daali, Youssef
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Development of a predictive score for potentially avoidable hospital readmissions for general internal medicine patientsBlanc, Anne-Laure; Fumeaux, Thierry; Stirnemann, Jérôme; Dupuis Lozeron, Elise; ... Bonnabry, Pascal
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Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva CocktailBosilkovska Weisskopf, Marija; Magliocco, Gaëlle; Desmeules, Jules Alexandre; Samer, Caroline Flora; Daali, Youssef
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Liquid Chromatography-Tandem Mass Spectrometry Method for Ticagrelor and its Active Metabolite Determination in Human Plasma: Application to a Pharmacokinetic StudyMarsousi, Niloufar; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef;
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Perioperative intravenous low-dose ketamine for neuropathic pain after major lower back surgery: A randomized, placebo-controlled studyCzarnetzki, Christoph; Desmeules, Jules Alexandre; Tessitore, Enrico; Faundez, Antonio; ... Tramer, Martin
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Phenotyping of human CYP450 enzymes by endobiotics: current knowledge and methodological approachesMagliocco, Gaëlle; Thomas, Aurélien; Desmeules, Jules Alexandre; Daali, Youssef;
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Physiologically-based pharmacokinetic modeling for the prediction of CYP2D6-mediated gene-drug-drug interactionsStorelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef;
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Pourquoi proposer la thérapie cognitivo-comportementale dans les douleurs chroniques ?Souche, Alain; Piguet, Valérie; Desmeules, Jules Alexandre; Cedraschi, Christine;
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Safety issues of pharmacological acute pain treatment in childrenRodieux, Frédérique; Piguet, Valérie; Desmeules, Jules Alexandre; Samer, Caroline Flora;
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Snapshot of proton pump inhibitors prescriptions in a tertiary care hospital in Switzerland: less is more?Lenoir, Camille; El Biali, Myriam; Luthy, Christophe; Grosgurin, Olivier; ... Rollason Gumprecht, Victoria
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Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modelingMagliocco, Gaëlle; Rodieux, Frédérique; Desmeules, Jules Alexandre; Samer, Caroline Flora; Daali, Youssef

Thesis supervisions

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Proteomic phenotyping of CNS cells exposed to inflammatory stimuli and opioidsDozio, Vito;

2018

Scientific Articles

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Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical PerspectivesStorelli, Flavia; Samer, Caroline Flora; Reny, Jean-Luc; Desmeules, Jules Alexandre; Daali, Youssef
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Genotype-sensitive reversible and time-dependent CYP2D6 inhibition in human liver microsomesStorelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef;
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Gestion de la douleur aiguë chez les patients sous traitements de substitution aux opioïdesManguzzi, Elena; Wainstein, Laura; Desmeules, Jules Alexandre; Broers, Barbara;
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Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active MetabolitesMarsousi, Niloufar; Daali, Youssef; Fontana, Pierre; Reny, Jean-Luc; ... Samer, Caroline Flora
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Phenotypic Assessment of Drug Metabolic Pathways and P-Glycoprotein in Patients Treated With Antidepressants in an Ambulatory SettingLloret-Linares, Célia; Bosilkovska Weisskopf, Marija; Daali, Youssef; Gex-Fabry, Marianne; ... Besson, Marie
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Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp softwareMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
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Prescription des opioïdes chez les patients vulnérables : les enfants et les personnes âgées. Recommandations pratiquesRodieux, Frédérique; Lloret-Linares, Célia; Piguet, Valérie; Desmeules, Jules Alexandre;
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Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case reportAebischer, Gaspard; Ing Lorenzini, Kuntheavy; Tomala, Simon; Desmeules, Jules Alexandre; ... Samer, Caroline Flora
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When the Safe Alternative Is Not That Safe: Tramadol Prescribing in ChildrenRodieux, Frédérique; Vutskits, Laszlo; Posfay Barbe, Klara; Habre, Walid; ... Samer, Caroline Flora

Thesis supervisions

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Understanding and predicting the association of intrinsic and extrinsic factors of pharmacokinetic variability in the context of precision medicine: impact of genetic polymorphisms on CYP2D6-mediated drug-drug interactionsStorelli, Flavia;

2017

Scientific Articles

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"Late" Withdrawal Syndrome after Carbamazepine In Utero Exposure in a CYP2C9 Slow Metabolizer NewbornPassia, Evangelia; Rock, Nathalie; Pfister, Riccardo; Ing Lorenzini, Kuntheavy; ... Samer, Caroline Flora
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Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferasesRomand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge
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Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study)Lloret-Linares, Célia; Daali, Youssef; Chevret, Sylvie; Nieto, Isabelle; ... Bellivier, Frank
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Hepatocyte Concentrations of Indocyanin Green (ICG) Reflects Transfer Rates Across Membrane TransportersCusin, Fabien; Azevedo, Liliana; Bonnaventure, Pierre; Desmeules, Jules Alexandre; ... Pastor, Catherine
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Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactionsStorelli, Flavia; Matthey, Alain; Lenglet, Sébastien; Thomas, Aurélien; ... Daali, Youssef
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PIM-Check: development of an international prescription-screening checklist designed by a Delphi method for internal medicine patientsDesnoyer, Aude; Blanc, Anne-Laure; Pourcher, Valérie; Besson, Marie; ... Guignard, Bertrand
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Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective studyLloret-Linares, Célia; Rollason Gumprecht, Victoria; Ing Lorenzini, Kuntheavy; Samer, Caroline Flora; ... Besson, Marie
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Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized MedicineMarsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;

Newspaper Articles

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Impact d’une réconciliation médicamenteuse par un pharmacien lors de l’admission dans un service de médecine interneSkalafouris, Christian; Guignard, Bertrand; Ing-Lorenzini, K.; Rollason, Victoria; ... Bonnabry, Pascal

Thesis supervisions

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CYP450-mediated drug-drug interactions: towards prediction and informed dose recommendation using physiologically-based pharmacokinetic (PBPK) modelingMarsousi, Niloufar;
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