2020

Scientific Articles

unige:143742	Cannabinoids and COVID-19	El Biali, Myriam; Broers, Barbara; Besson, Marie; Desmeules, Jules Alexandre;
unige:144205	Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in Children	Dilo, Ana; Daali, Youssef; Desmeules, Jules Alexandre; Chalandon, Yves; ... Ansari Djaberi, Marc Georges
unige:149715	Deep proteomics and phosphoproteomics reveal novel biological pathways perturbed by morphine, morphine-3-glucuronide and morphine-6-glucuronide in human astrocytes	Dozio, Vito; Daali, Youssef; Desmeules, Jules Alexandre; Sanchez, Jean-Charles;
unige:149706	Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study	Rollason, Victoria; Lloret-linaret, Célia; Ing Lorenzini, Kuntheavy; Daali, Youssef; ... Desmeules, Jules Alexandre
unige:149695	GABAergic modulation of secondary hyperalgesia: A randomized controlled 4-way crossover trial with the α2-subunit preferring GABA positive allosteric modulator, N-desmethyl-clobazam in healthy volunteers	Matthey, Alain; Daali, Youssef; Curtin, François; Poncet, Antoine; ... Besson, Marie
unige:149687	Gender Differences in Cardiovascular Pharmacotherapy-the Example of Hypertension: A Mini Review	Kalibala, Jacklean; Pechere, Antoinette; Desmeules, Jules Alexandre;
unige:149068	Impact of acute inflammation on cytochromes P450 activity assessed by the Geneva Cocktail	Lenoir, Camille; Daali, Youssef; Rollason, Victoria; Curtin, François; ... Samer, Caroline Flora
unige:149069	Outcomes of drug exposition during pregnancy: Analysis from a teratology information service	Lenoir, Camille; Boumaiza, Sabrina; Ing Lorenzini, Kuntheavy; Boulvain, Michel; ... Rollason, Victoria
unige:146848	Pain interventions in adults with intellectual disability: A scoping review and pharmacological considerations	Lonchampt, Sophie; Gerber, Fabienne; Aubry, Jean-Michel; Desmeules, Jules Alexandre; ... Besson, Marie
unige:141697	Safety of the Geneva Cocktail, a Cytochrome P450 and P-Glycoprotein Phenotyping Cocktail, in Healthy Volunteers from Three Different Geographic Origins	Rollason, Victoria; Mouterde, Médéric; Daali, Youssef; Čížková, Martina; ... Desmeules, Jules Alexandre
unige:149436	Single center observational study on the role of demoralization and meaning in life in influencing suicidal ideation among patients affected by chronic pain (DEMiL study): A study protocol	Costanza, Alessandra; Chytas, Vasileios; Mazzola, Viridiana; Piguet, Valérie; ... Cedraschi, Christine
unige:145583	TOP-ID: a Delphi technique-guided development of a prescription and deprescription tool for adults with intellectual disabilities	Lonchampt, Sophie; Gerber, Fabienne Maria Y.; Aubry, Jean-Michel; Desmeules, Jules Alexandre; ... Kosel, Markus Mathaus

Professional Articles

unige:146028

Opioïdes chez les patients âgés: Faux-amis ?

El Biali, Myriam; Desmeules, Jules Alexandre; Besson, Marie;

2019

Scientific Articles

unige:118580	A case report of cholinergic rebound syndrome following abrupt low-dose clozapine discontinuation in a patient with type I bipolar affective disorder	Galova, Andréa; Berney, Patricia Elisabeth; Desmeules, Jules Alexandre; Sergentanis, Ioannis; Besson, Marie
unige:128196	Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxins	Samer, Caroline Flora; Gloor, Yvonne Sylvia; Rollason Gumprecht, Victoria; Guessous, Idris; ... Daali, Youssef
unige:126844	Development of a predictive score for potentially avoidable hospital readmissions for general internal medicine patients	Blanc, Anne-Laure; Fumeaux, Thierry; Stirnemann, Jérôme; Dupuis Lozeron, Elise; ... Bonnabry, Pascal
unige:128192	Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva Cocktail	Bosilkovska Weisskopf, Marija; Magliocco, Gaëlle; Desmeules, Jules Alexandre; Samer, Caroline Flora; Daali, Youssef
unige:134650	Liquid Chromatography-Tandem Mass Spectrometry Method for Ticagrelor and its Active Metabolite Determination in Human Plasma: Application to a Pharmacokinetic Study	Marsousi, Niloufar; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef;
unige:127240	Perioperative intravenous low-dose ketamine for neuropathic pain after major lower back surgery: A randomized, placebo-controlled study	Czarnetzki, Christoph; Desmeules, Jules Alexandre; Tessitore, Enrico; Faundez, Antonio; ... Tramer, Martin
unige:121245	Phenotyping of human CYP450 enzymes by endobiotics: current knowledge and methodological approaches	Magliocco, Gaëlle; Thomas, Aurélien; Desmeules, Jules Alexandre; Daali, Youssef;
unige:121056	Physiologically-based pharmacokinetic modeling for the prediction of CYP2D6-mediated gene-drug-drug interactions	Storelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef;
unige:134665	Pourquoi proposer la thérapie cognitivo-comportementale dans les douleurs chroniques ?	Souche, Alain; Piguet, Valérie; Desmeules, Jules Alexandre; Cedraschi, Christine;
unige:120073	Safety issues of pharmacological acute pain treatment in children	Rodieux, Frédérique; Piguet, Valérie; Desmeules, Jules Alexandre; Samer, Caroline Flora;
unige:128198	Snapshot of proton pump inhibitors prescriptions in a tertiary care hospital in Switzerland: less is more?	Lenoir, Camille; El Biali, Myriam; Luthy, Christophe; Grosgurin, Olivier; ... Rollason Gumprecht, Victoria
unige:128193	Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling	Magliocco, Gaëlle; Rodieux, Frédérique; Desmeules, Jules Alexandre; Samer, Caroline Flora; Daali, Youssef

Thesis supervisions

unige:121673

Proteomic phenotyping of CNS cells exposed to inflammatory stimuli and opioids

Dozio, Vito;

2018

Scientific Articles

unige:110999	Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives	Storelli, Flavia; Samer, Caroline Flora; Reny, Jean-Luc; Desmeules, Jules Alexandre; Daali, Youssef
unige:110974	Genotype-sensitive reversible and time-dependent CYP2D6 inhibition in human liver microsomes	Storelli, Flavia; Desmeules, Jules Alexandre; Daali, Youssef;
unige:115338	Gestion de la douleur aiguë chez les patients sous traitements de substitution aux opioïdes	Manguzzi, Elena; Wainstein, Laura; Desmeules, Jules Alexandre; Broers, Barbara;
unige:111012	Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites	Marsousi, Niloufar; Daali, Youssef; Fontana, Pierre; Reny, Jean-Luc; ... Samer, Caroline Flora
unige:115534	Phenotypic Assessment of Drug Metabolic Pathways and P-Glycoprotein in Patients Treated With Antidepressants in an Ambulatory Setting	Lloret-Linares, Célia; Bosilkovska Weisskopf, Marija; Daali, Youssef; Gex-Fabry, Marianne; ... Besson, Marie
unige:98710	Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software	Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;
unige:115334	Prescription des opioïdes chez les patients vulnérables : les enfants et les personnes âgées. Recommandations pratiques	Rodieux, Frédérique; Lloret-Linares, Célia; Piguet, Valérie; Desmeules, Jules Alexandre;
unige:110991	Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report	Aebischer, Gaspard; Ing Lorenzini, Kuntheavy; Tomala, Simon; Desmeules, Jules Alexandre; ... Samer, Caroline Flora
unige:107473	When the Safe Alternative Is Not That Safe: Tramadol Prescribing in Children	Rodieux, Frédérique; Vutskits, Laszlo; Posfay Barbe, Klara; Habre, Walid; ... Samer, Caroline Flora

Thesis supervisions

unige:114515

Understanding and predicting the association of intrinsic and extrinsic factors of pharmacokinetic variability in the context of precision medicine: impact of genetic polymorphisms on CYP2D6-mediated drug-drug interactions

Storelli, Flavia;

2017

Scientific Articles

unige:98712	"Late" Withdrawal Syndrome after Carbamazepine In Utero Exposure in a CYP2C9 Slow Metabolizer Newborn	Passia, Evangelia; Rock, Nathalie; Pfister, Riccardo; Ing Lorenzini, Kuntheavy; ... Samer, Caroline Flora
unige:90072	Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases	Romand, Stéphanie Anne; Spaggiari, Dany; Marsousi, Niloufar; Samer, Caroline Flora; ... Rudaz, Serge
unige:111045	Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study)	Lloret-Linares, Célia; Daali, Youssef; Chevret, Sylvie; Nieto, Isabelle; ... Bellivier, Frank
unige:89991	Hepatocyte Concentrations of Indocyanin Green (ICG) Reflects Transfer Rates Across Membrane Transporters	Cusin, Fabien; Azevedo, Liliana; Bonnaventure, Pierre; Desmeules, Jules Alexandre; ... Pastor, Catherine
unige:99762	Impact of CYP2D6 functional allelic variations on phenoconversion and drug-drug interactions	Storelli, Flavia; Matthey, Alain; Lenglet, Sébastien; Thomas, Aurélien; ... Daali, Youssef
unige:98702	PIM-Check: development of an international prescription-screening checklist designed by a Delphi method for internal medicine patients	Desnoyer, Aude; Blanc, Anne-Laure; Pourcher, Valérie; Besson, Marie; ... Guignard, Bertrand
unige:86303	Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study	Lloret-Linares, Célia; Rollason Gumprecht, Victoria; Ing Lorenzini, Kuntheavy; Samer, Caroline Flora; ... Besson, Marie
unige:97051	Usefulness of PBPK Modeling in Incorporation of Clinical Conditions in Personalized Medicine	Marsousi, Niloufar; Desmeules, Jules Alexandre; Rudaz, Serge; Daali, Youssef;

Newspaper Articles

unige:144976

Impact d’une réconciliation médicamenteuse par un pharmacien lors de l’admission dans un service de médecine interne

Skalafouris, Christian; Guignard, Bertrand; Ing-Lorenzini, K.; Rollason, Victoria; ... Bonnabry, Pascal

Thesis supervisions

unige:100121

CYP450-mediated drug-drug interactions: towards prediction and informed dose recommendation using physiologically-based pharmacokinetic (PBPK) modeling

Marsousi, Niloufar;

2016

Scientific Articles

unige:86304	Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach	Marsousi, Niloufar; Samer, Caroline Flora; Fontana, Pierre; Reny, Jean-Luc; ... Daali, Youssef
unige:86308	Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method	Bosilkovska Weisskopf, Marija; Samer, Caroline Flora; Deglon, Julien; Thomas, Aurélien; ... Daali, Youssef
unige:86301	Intestinal permeability and P-glycoprotein-mediated efflux transport of ticagrelor in Caco-2 monolayer cells	Marsousi, Niloufar; Doffey-Lazeyras, Fabienne; Rudaz, Serge; Desmeules, Jules Alexandre; Daali, Youssef
unige:86299	Le coût, ce n'est pas tout…à propos des médicaments génériques	Piguet, Valérie; D'Incau, Stéphanie; Besson, Marie; Desmeules, Jules Alexandre; Cedraschi, Christine