Gabay, Cem

 
 
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2018

Scientific Articles

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Biological agents in the management of adult-onset Still's diseaseGirard-Guyonvarc'h, Charlotte; Gabay, Cem;
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Identification of sarilumab pharmacodynamic and predictive markers in patients with inadequate response to TNF inhibition: a biomarker substudy of the phase 3 TARGET studyGabay, Cem; Msihid, Jérôme; Zilberstein, Moshe; Paccard, Caroline; ... Boyapati, Anita
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Incidence and prevalence of major adverse cardiovascular events in rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritisLauper, Kim; Courvoisier, Delphine S; Chevallier, Paola; Finckh, Axel; Gabay, Cem
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Inflammasome Adaptor ASC Suppresses Apoptosis of Gastric Cancer Cells by an IL18-Mediated Inflammation-Independent MechanismDeswaerte, Virginie; Nguyen, Paul; West, Alison; Browning, Alison F; ... Jenkins, Brendan J
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Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndromeWeiss, Eric S; Girard-Guyonvarc'h, Charlotte; Holzinger, Dirk; de Jesus, Adriana A; ... Canna, Scott W
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Nanocrystal-Polymer Particles: Extended Delivery Carriers for Osteoarthritis TreatmentMaudens, Pierre Marc Xavier; Seemayer, Christian Alexander; Thauvin, Cédric; Gabay, Cem; ... Allémann, Eric
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Open-label, multicentre, dose-escalating phase II clinical trial on the safety and efficacy of tadekinig alfa (IL-18BP) in adult-onset Still's diseaseGabay, Cem; Fautrel, Bruno; Rech, Jürgen; Spertini, François; ... Schiffrin, Eduardo Jorge
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Regulation and function of interleukin-36 cytokinesBassoy, Esen Yonca; Towne, Jennifer E; Gabay, Cem;
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Unopposed IL-18 signaling leads to severe TLR9-induced macrophage activation syndrome in miceGirard-Guyonvarc'h, Charlotte; Palomo, Jennifer; Martin, Praxedis Sina; Rodriguez, Emiliana; ... Gabay, Cem
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Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selectionLloyd, Katy A; Steen, Johanna; Amara, Khaled; Titcombe, Philip J; ... Grönwall, Caroline
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β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin SecretionBöni-Schnetzler, Marianne; Häuselmann, Stéphanie P.; Dalmas, Elise; Meier, Daniel T.; ... Donath, Marc Y.

Thesis supervisions

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Le risque cardiovasculaire dans la polyarthrite rhumatoïde, la spondylarthrite axiale et le rhumatisme psoriasiqueLauper, Kim;
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L’effet des traitements de fond conventionnels synthétiques en termes d’efficacité clinique et de la survie des antagonistes du facteur de nécrose tumorale dans une cohorte des patients avec une spondylarthrite axialeNissen, Michael John;

2017

Scientific Articles

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Cardiovascular risk in patients with rheumatoid arthritisLauper, Kim; Gabay, Cem;
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Deficiency in IL-1 Receptor Type 2 Aggravates K/BxN Serum Transfer-Induced Arthritis in Mice but Has No Impact on Systemic Inflammatory ResponsesMartin, Praxedis Sina; Palmer-Lourenco, Gaby; Rodriguez, Emiliana; Seemayer, Christian Alexander; ... Gabay, Cem
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EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 updateSmolen, Josef S; Landewé, Robert; Bijlsma, Johannes; Burmester, Gerd; ... van der Heijde, Désirée
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Female hormonal factors and the development of anti-citrullinated protein antibodies in women at risk of rheumatoid arthritisAlpizar Rodriguez, Deshire; Mueller, Rüdiger B; Möller, Burkhard; Dudler, Jean; ... Finckh, Axel
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Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of OsteoclastogenesisSantiago, Llipsy; Menaa, Cheikh; Arias, Maykel; Martin, Praxedis Sina; ... Froelich, Christopher J
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IL-38 overexpression induces anti-inflammatory effects in mice arthritis models and in human macrophages in vitroBoutet, Marie-Astrid; Najm, Aurélie; Bart, Géraldine; Brion, Régis; ... Le Goff, Benoit
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Impact of tocilizumab monotherapy on patient-reported outcomes in patients with rheumatoid arthritis from two randomised controlled trialsStrand, Vibeke; Michalska, Margaret; Birchwood, Christine; Pei, Jinglan; ... Jones, Graeme
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International and multidisciplinary expert recommendations for the use of biologics in systemic lupus erythematosusKleinmann, Jean-François; Tubach, Florence; Le Guern, Véronique; Mathian, Alexis; ... Gottenberg, Jacques-Eric
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Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibitionCanna, Scott W; Girard, Charlotte; Malle, Louise; de Jesus, Adriana; ... Behrens, Edward M
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Presence of IL-17 in synovial fluid identifies a potential inflammatory osteoarthritic phenotypeSnelling, Sarah J B; Bas, Sylvette; Puskas, Gabor Janos; Dakin, Stephanie G; ... Lübbeke, Anne
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Rheumatoid arthritis: from basic findings and clinical manifestations to future therapiesHasler, Paul; Gabay, Cem;
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Rituximab Retreatment in Rheumatoid Arthritis in a Real-life Cohort: Data from the CERERRA CollaborationChatzidionysiou, Katerina; Lie, Elisabeth; Lukina, Galina; Hetland, Merete L; ... van Vollenhoven, Ronald
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Salt-inducible kinases (SIK) inhibition reduces RANKL-induced osteoclastogenesisLombardi, Maria Stella; Gillieron, Corine; Berkelaar, Majoska; Gabay, Cem;
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The perioperative use of synthetic and biological disease-modifying antirheumatic drugs in patients with rheumatoid arthritisFleury, Gregory Stéphane; Mania, Sylvano Anis; Hannouche, Didier; Gabay, Cem;
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The prevalence of anticitrullinated protein antibodies increases with age in healthy individuals at risk for rheumatoid arthritisAlpizar Rodriguez, Deshire; Brulhart, Laure Sophie; Mueller, Ruediger B; Möller, Burkhard; ... Finckh, Axel
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The role of female hormonal factors in the development of rheumatoid arthritisAlpizar Rodriguez, Deshire; Pluchino, Nicola; Canny, Geraldine; Gabay, Cem; Finckh, Axel
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Treatment efficacy and methotrexate-related toxicity in patients with rheumatoid arthritis receiving methotrexate in combination with adalimumabBurmester, Gerd R; Kaeley, Gurjit S; Kavanaugh, Arthur F; Gabay, Cem; ... Kalabic, Jasmina

Thesis supervisions

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Comparaison des effets de l'IL-1 et de l'IL-36 sur les cellules immunitaires humainesDietrich, Damien;

2016

Scientific Articles

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A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated diseaseHatterer, Eric; Shang, Limin; Simonet, Pierre; Herren, Suzanne; ... De Min, Cristina
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Comparison of lipid and lipid-associated cardiovascular risk marker changes after treatment with tocilizumab or adalimumab in patients with rheumatoid arthritisGabay, Cem; McInnes, Iain B; Kavanaugh, Arthur; Tuckwell, Katie; ... Sattar, Naveed
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Distinct expression of interleukin (IL)-36α, β and γ, their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and Crohn's diseaseBoutet, M-A; Bart, G; Penhoat, M; Amiaud, J; ... Blanchard, F
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Effect of particle size on the biodistribution of nano- and microparticles following intra-articular injection in micePradal, Julie; Maudens, Pierre Marc Xavier; Gabay, Cem; Seemayer, Christian Alexander; ... Allémann, Eric
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Effectiveness of tocilizumab with and without synthetic disease-modifying antirheumatic drugs in rheumatoid arthritis: results from a European collaborative studyGabay, Cem; Riek, Myriam; Hetland, Merete Lund; Hauge, Ellen-Margrethe; ... Kvien, Tore K
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Effectiveness of two different doses of rituximab for the treatment of rheumatoid arthritis in an international cohort: data from the CERERRA collaborationChatzidionysiou, Katerina; Lie, Elisabeth; Nasonov, Evgeny; Lukina, Galina; ... van Vollenhoven, Ronald F
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Elevated serum levels of free interleukin-18 in adult-onset Still's diseaseGirard, Charlotte; Rech, Jürgen; Brown, Michael; Allali, Danièle; ... Gabay, Cem
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IL-1R1-MyD88 axis elicits papain-induced lung inflammationAgoro, Rafiou; Piotet-Morin, Julie; Palomo, Jennifer; Michaudel, Chloé; ... Couturier-Maillard, Aurélie
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IL-36-Induced Toxicity in Neonatal Mice Involves TNF-α Production by Liver Myeloid CellsPalomo, Jennifer; Mastelic-Gavillet, Beatris; Woldt, Estelle; Troccaz, Sabina; ... Gabay, Cem
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Interleukin-36 potently stimulates human M2 macrophages, Langerhans cells and keratinocytes to produce pro-inflammatory cytokinesDietrich, Damien; Martin, Praxedis Sina; Flacher, Vincent; Sun, Yu; ... Gabay, Cem
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Rituximab done: what's next in rheumatoid arthritis? A European observational longitudinal study assessing the effectiveness of biologics after rituximab treatment in rheumatoid arthritisWalker, Ulrich A; Jaeger, Veronika K; Chatzidionysiou, Katerina; Hetland, Merete L; ... Gabay, Cem
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SIK inhibition in human myeloid cells modulates TLR and IL-1R signaling and induces an anti-inflammatory phenotypeLombardi, Maria Stella; Gillieron, Corine; Dietrich, Damien; Gabay, Cem;
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The Effect of Comedication With a Conventional Synthetic Disease-Modifying Antirheumatic Drug on Drug Retention and Clinical Effectiveness of Anti-Tumor Necrosis Factor Therapy in Patients With Axial SpondyloarthritisNissen, Michael John; Ciurea, Adrian; Bernhard, Jürg; Tamborrini, Giorgio; ... Finckh, Axel
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