TRIM5 is an innate immune sensor for the retrovirus capsid lattice
ContributorsPertel, Thomas; Hausmann, Stéphane; Morger, Damien; Züger, Sara; Guerra, Jessica; Lascano Maillard, Maria Josefina; Reinhard, Christian; Santoni, Federico; Uchil, Pradeep D; Chatel, Laurence; Bisiaux, Aurélie; Albert, Matthew L; Strambio-De-Castillia, Caterina; Mothes, Walther; Pizzato, Massimo; Grütter, Markus G; Luban, Jeremy
Published inNature, vol. 472, no. 7343, p. 361-365
Publication date2011
Abstract
Keywords
- Capsid/chemistry/immunology
- Carrier Proteins/genetics/immunology/metabolism
- Cell Line
- Enzyme Activation
- HEK293 Cells
- HIV-1/chemistry/immunology
- Humans
- Immunity, Innate/immunology
- Lipopolysaccharides/immunology/pharmacology
- MAP Kinase Kinase Kinases/metabolism
- NF-kappa B/metabolism
- Protein Binding
- Receptors, Pattern Recognition/immunology/metabolism
- Retroviridae/chemistry/immunology
- Signal Transduction/drug effects/immunology
- Transcription Factor AP-1/metabolism
- Transcription Factors/metabolism
- Ubiquitin/metabolism
- Ubiquitin-Conjugating Enzymes/metabolism
- Ubiquitin-Protein Ligases/genetics/immunology/metabolism
Affiliation entities
Citation (ISO format)
PERTEL, Thomas et al. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. In: Nature, 2011, vol. 472, n° 7343, p. 361–365. doi: 10.1038/nature09976
Main files (1)
Article (Published version)
Identifiers
- PID : unige:92031
- DOI : 10.1038/nature09976
- PMID : 21512573
ISSN of the journal0028-0836