Determination of the absolute configuration of chiral cyclic alcohols using diamine derivatizing agents by 31P NMR spectroscopy

Chauvin, Anne-Sophie; Bernardinelli, Gérald Hugues; Alexakis, Alexandre

doi:10.1016/j.tetasy.2006.07.042

Scientific article

English

Determination of the absolute configuration of chiral cyclic alcohols using diamine derivatizing agents by 31P NMR spectroscopy

ContributorsChauvin, Anne-Sophie; Bernardinelli, Gérald Hugues; Alexakis, Alexandre

Published inTetrahedron: asymmetry, vol. 17, no. 15, p. 2203-2209

Publication date2006

Abstract

The absolute configuration and enantiomeric excess of chiral cyclic alcohols can be predicted from the 31P NMR spectra of the two diastereoisomers obtained with organophosphorus diamino-derivatizing agents (CDAs) and the chiral secondary alcohol, according to a simplified model taking into account the spatial location of the substituents of the chiral alcohol center and the 31P NMR signals of the two diastereoisomers.

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

CHAUVIN, Anne-Sophie, BERNARDINELLI, Gérald Hugues, ALEXAKIS, Alexandre. Determination of the absolute configuration of chiral cyclic alcohols using diamine derivatizing agents by 31P NMR spectroscopy. In: Tetrahedron: asymmetry, 2006, vol. 17, n° 15, p. 2203–2209. doi: 10.1016/j.tetasy.2006.07.042

Article (Published version)

Identifiers

PID : unige:8116
DOI : 10.1016/j.tetasy.2006.07.042

Journal ISSN0957-4166

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Determination of the absolute configuration of chiral cyclic alcohols using diamine derivatizing agents by 31P NMR spectroscopy

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