Tandem asymmetric conjugate addition-enolacetates formation of enantiomerically enriched zinc and aluminium enolates

Vuagnoux-D'Augustin De, Magali; Alexakis, Alexandre

doi:10.1016/j.tetlet.2007.07.220

Scientific article

English

Tandem asymmetric conjugate addition-enolacetates formation of enantiomerically enriched zinc and aluminium enolates

ContributorsVuagnoux-D'Augustin De, Magali; Alexakis, Alexandre

Published inTetrahedron letters, vol. 48, no. 41, p. 7408-7412

Publication date2007

Abstract

The metal enolates, resulting from the copper-catalyzed enantioselective conjugate addition of organometallic reagents (Et2Zn or R3Al) to cyclic and acyclic enones are quantitatively trapped as enolacetates with acetic anhydride.

Keywords

Michael addition
Copper
Enolacetate

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

VUAGNOUX-D’AUGUSTIN DE, Magali, ALEXAKIS, Alexandre. Tandem asymmetric conjugate addition-enolacetates formation of enantiomerically enriched zinc and aluminium enolates. In: Tetrahedron letters, 2007, vol. 48, n° 41, p. 7408–7412. doi: 10.1016/j.tetlet.2007.07.220

Article (Published version)

Identifiers

PID : unige:8108
DOI : 10.1016/j.tetlet.2007.07.220

Journal ISSN0040-4039

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Tandem asymmetric conjugate addition-enolacetates formation of enantiomerically enriched zinc and aluminium enolates

The metal enolates, resulting from the copper-catalyzed enantioselective conjugate addition of organometallic reagents (Et2Zn or R3Al) to cyclic and acyclic enones are quantitatively trapped as enolacetates with acetic anhydride.

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