Determination of enantiomeric purity of hydroxy biaryls using 1H and 31P NMR on their diazaphospholidine derivatives

Alexakis, Alexandre; Frutos, Juan C.; Mangeney, Pierre; Meyers, A.I.; Moorlag, Henk

doi:10.1016/S0040-4039(00)77044-4

Scientific article

Letter

English

Determination of enantiomeric purity of hydroxy biaryls using 1H and 31P NMR on their diazaphospholidine derivatives

ContributorsAlexakis, Alexandre; Frutos, Juan C.; Mangeney, Pierre; Meyers, A.I.; Moorlag, Henk

Published inTetrahedron letters, vol. 35, no. 29, p. 5125-5128

Publication date1994

Abstract

Chiral biaryl alcohols were readily transformed in a single step, with chiral non-racemic 1,2-diamines, PCl3, and sulfur in CDCl3 - all in a NMR tube - to their diastereomeric diazaphospholidines and their diastereomeric ratios (also ee's) assessed directly.

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Not a UNIGE publication

Citation (ISO format)

ALEXAKIS, Alexandre et al. Determination of enantiomeric purity of hydroxy biaryls using 1H and 31P NMR on their diazaphospholidine derivatives. In: Tetrahedron letters, 1994, vol. 35, n° 29, p. 5125–5128. doi: 10.1016/S0040-4039(00)77044-4

Article (Published version)

Identifiers

PID : unige:8085
DOI : 10.1016/S0040-4039(00)77044-4

Journal ISSN0040-4039

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Determination of enantiomeric purity of hydroxy biaryls using 1H and 31P NMR on their diazaphospholidine derivatives

Chiral biaryl alcohols were readily transformed in a single step, with chiral non-racemic 1,2-diamines, PCl3, and sulfur in CDCl3 - all in a NMR tube - to their diastereomeric diazaphospholidines and their diastereomeric ratios (also ee's) assessed directly.

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