Enantioselective catalytic rearrangement of cyclohexene oxide with new homochiral bis-lithium amide bases

Equey, Olivier; Alexakis, Alexandre

doi:10.1016/j.tetasy.2004.02.030

Scientific article

English

Enantioselective catalytic rearrangement of cyclohexene oxide with new homochiral bis-lithium amide bases

ContributorsEquey, Olivier; Alexakis, Alexandre

Published inTetrahedron: asymmetry, vol. 15, no. 7, p. 1069-1072

Publication date2004

Abstract

Cyclohexene oxide can be rearranged with good levels of induction (up to 68% ee) with substoichiometric amounts of chiral bases derived from readily available diamines. The influence of the steric bulk of the amine substituents on the rearrangement enantioselectivity has also been studied.

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

EQUEY, Olivier, ALEXAKIS, Alexandre. Enantioselective catalytic rearrangement of cyclohexene oxide with new homochiral bis-lithium amide bases. In: Tetrahedron: asymmetry, 2004, vol. 15, n° 7, p. 1069–1072. doi: 10.1016/j.tetasy.2004.02.030

Article (Published version)

Identifiers

PID : unige:8056
DOI : 10.1016/j.tetasy.2004.02.030

Journal ISSN0957-4166

646views

0downloads

Creation21/06/2010 14:15:56

First validation21/06/2010 14:15:56

Update time14/03/2023 15:47:53

Status update14/03/2023 15:47:53

Last indexation10/06/2025 21:36:08

Archive ouverte UNIGE

Enantioselective catalytic rearrangement of cyclohexene oxide with new homochiral bis-lithium amide bases

Cyclohexene oxide can be rearranged with good levels of induction (up to 68% ee) with substoichiometric amounts of chiral bases derived from readily available diamines. The influence of the steric bulk of the amine substituents on the rearrangement enantioselectivity has also been studied.

Technical informations