A highly effective phosphoramidite ligand for asymmetric allylic substitution

Tissot-Croset, Karine; Polet, Damien; Alexakis, Alexandre

doi:10.1002/anie.200353744

Scientific article

English

A highly effective phosphoramidite ligand for asymmetric allylic substitution

ContributorsTissot-Croset, Karine; Polet, Damien; Alexakis, Alexandre

Published inAngewandte Chemie, vol. 43, no. 18, p. 2426-2428

Publication date2004

Abstract

Very high enantioselectivity has been achieved both in the copper-catalyzed alkylation of allylic substrates by Grignard and organozinc reagents and in the iridium-catalyzed amination of cinnamyl carbonate by employing a very efficient phosphoramidite ligand

Keywords

Allylation
Asymmetric catalysis
Chiral auxiliaries
Copper
Iridium
Magnesium

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

TISSOT-CROSET, Karine, POLET, Damien, ALEXAKIS, Alexandre. A highly effective phosphoramidite ligand for asymmetric allylic substitution. In: Angewandte Chemie, 2004, vol. 43, n° 18, p. 2426–2428. doi: 10.1002/anie.200353744

Article (Published version)

Identifiers

PID : unige:8048
DOI : 10.1002/anie.200353744

Journal ISSN1433-7851

653views

2downloads

Creation21/06/2010 14:15:52

First validation21/06/2010 14:15:52

Update time14/03/2023 15:47:51

Status update14/03/2023 15:47:51

Last indexation10/06/2025 21:35:59

Archive ouverte UNIGE

A highly effective phosphoramidite ligand for asymmetric allylic substitution

Very high enantioselectivity has been achieved both in the copper-catalyzed alkylation of allylic substrates by Grignard and organozinc reagents and in the iridium-catalyzed amination of cinnamyl carbonate by employing a very efficient phosphoramidite ligand

Technical informations