SimplePhos monodentate ligands: Synthesis and application in copper-catalysed reactions

Palais, Laetitia; Mikhel, Igor; Bournaud, Chloee Julie; Micouin, Laurent; Falciola, Caroline Alexandra; Vuagnoux-D'Augustin De, Magali; Rosset, Stéphane; Bernardinelli, Gérald Hugues; Alexakis, Alexandre

doi:10.1002/anie.200702186

Scientific article

English

SimplePhos monodentate ligands: Synthesis and application in copper-catalysed reactions

ContributorsPalais, Laetitia; Mikhel, Igor; Bournaud, Chloee Julie; Micouin, Laurent; Falciola, Caroline Alexandra; Vuagnoux-D'Augustin De, Magali; Rosset, Stéphane; Bernardinelli, Gérald Hugues; Alexakis, Alexandre

Published inAngewandte Chemie, vol. 46, no. 39, p. 7462-7465

Publication date2007

Abstract

A simple choice: Ligands termed SimplePhos (L*), based on a chiral amino and flexible aryl groups on the phosphorus atom, induce high enantioselectivity in the copper-catalyzed conjugate addition and allylic substitution of dialkyl zinc and trialkyl aluminum reagents (see scheme; CuTC=copper thiophene carboxylate).

Keywords

Asymmetric catalysis
Conjugate addition
Copper
Enones
P ligands

Affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

Citation (ISO format)

PALAIS, Laetitia et al. SimplePhos monodentate ligands: Synthesis and application in copper-catalysed reactions. In: Angewandte Chemie, 2007, vol. 46, n° 39, p. 7462–7465. doi: 10.1002/anie.200702186

Article (Published version)

Identifiers

PID : unige:8017
DOI : 10.1002/anie.200702186
PMID : 17702075

Journal ISSN1433-7851

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SimplePhos monodentate ligands: Synthesis and application in copper-catalysed reactions

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