Methylation of Serotonin Receptor 3a in ADHD, Borderline Personality, and Bipolar Disorders: Link with Severity of the Disorders and Childhood Maltreatment

Perroud, Nader Ali; Zewdie Wondimu, Seblewongel; Stenz, Ludwig; Adouan, Wafae; Bavamian Suter, Sabine; Prada, Paco Boris; Nicastro, Rosetta; Hasler, Roland; Nallet, Audrey; Piguet, Camille Marie; Giacobino, Ariane; Aubry, Jean-Michel; Dayer, Alexandre

doi:10.1002/da.22406

Scientific article

English

Methylation of Serotonin Receptor 3a in ADHD, Borderline Personality, and Bipolar Disorders: Link with Severity of the Disorders and Childhood Maltreatment

ContributorsPerroud, Nader Ali

; Zewdie Wondimu, Seblewongel; Stenz, Ludwig

; Adouan, Wafae; Bavamian Suter, Sabine; Prada, Paco Boris; Nicastro, Rosetta; Hasler, Roland; Nallet, Audrey; Piguet, Camille Marie

; Giacobino, Ariane; Aubry, Jean-Michel; Dayer, Alexandre

Published inDepression and anxiety, vol. 33, no. 1, p. 45-55

Publication date2016

Abstract

Serotonin 3A receptor (5-HT3A R) is associated at the genetic and epigenetic levels with a variety of psychiatric disorders and interacts with early-life stress such as childhood maltreatment. We studied the impact of childhood maltreatment on the methylation status of the 5-HT3A R and its association with clinical severity outcomes in relation with a functional genetic polymorphism.

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Citation (ISO format)

PERROUD, Nader Ali et al. Methylation of Serotonin Receptor 3a in ADHD, Borderline Personality, and Bipolar Disorders: Link with Severity of the Disorders and Childhood Maltreatment. In: Depression and anxiety, 2016, vol. 33, n° 1, p. 45–55. doi: 10.1002/da.22406

Article (Published version)

Identifiers

PID : unige:78757
DOI : 10.1002/da.22406
PMID : 26350166

Journal ISSN1091-4269

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Methylation of Serotonin Receptor 3a in ADHD, Borderline Personality, and Bipolar Disorders: Link with Severity of the Disorders and Childhood Maltreatment

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