Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments

Quteineh, Lina; Vandenberghe, Frederik; Saigi Morgui, Nuria; Delacrétaz, Aurélie; Choong, Eva; Gholam-Rezaee, Mehdi; Magistretti, Pierre; Bondolfi, Guido; Von Gunten, Armin; Preisig, Martin; Castelao, Enrique; Vollenweider, Peter; Waeber, Gerard; Bochud, Murielle; Kutalik, Zoltán; Conus, Philippe; Eap, Chin Bin

doi:10.1097/FPC.0000000000000131

Scientific article

English

Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments

ContributorsQuteineh, Lina; Vandenberghe, Frederik; Saigi Morgui, Nuria; Delacrétaz, Aurélie; Choong, Eva; Gholam-Rezaee, Mehdi; Magistretti, Pierre; Bondolfi, Guido; Von Gunten, Armin; Preisig, Martin; Castelao, Enrique; Vollenweider, Peter; Waeber, Gerard; Bochud, Murielle; Kutalik, Zoltán; Conus, Philippe; Eap, Chin Bin

Published inPharmacogenetics and genomics, vol. 25, no. 5, p. 246-258

Publication date2015

Abstract

Metabolic syndrome (MetS) associated with psychiatric disorders and psychotropic treatments represents a major health issue. 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is an enzyme that catalyzes tissue regeneration of active cortisol from cortisone. Elevated enzymatic activity of 11β-HSD1 may lead to the development of MetS.

Affiliation entities

Research groups

Médecine psychosomatique, neurosciences cliniques et mindfulness (690)

Citation (ISO format)

QUTEINEH, Lina et al. Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments. In: Pharmacogenetics and genomics, 2015, vol. 25, n° 5, p. 246–258. doi: 10.1097/FPC.0000000000000131

Article (Published version)

Identifiers

PID : unige:78753
DOI : 10.1097/FPC.0000000000000131
PMID : 25751397

Journal ISSN1744-6872

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Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments

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