Scientific article
OA Policy
English

International trial of the Edmonton protocol for islet transplantation

Published inThe New England journal of medicine, vol. 355, no. 13, p. 1318-1330
Publication date2006
Abstract

Islet transplantation offers the potential to improve glycemic control in a subgroup of patients with type 1 diabetes mellitus who are disabled by refractory hypoglycemia. We conducted an international, multicenter trial to explore the feasibility and reproducibility of islet transplantation with the use of a single common protocol (the Edmonton protocol).

Keywords
  • Adult
  • Blood Glucose/metabolism
  • C-Peptide/blood
  • Diabetes Mellitus, Type 1/blood/therapy
  • Feasibility Studies
  • Follow-Up Studies
  • Humans
  • Hypoglycemic Agents/therapeutic use
  • Immunosuppressive Agents/adverse effects/therapeutic use
  • Infusions, Intravenous
  • Insulin/secretion/therapeutic use
  • Islets of Langerhans Transplantation/adverse effects/methods/standards
  • Isoantibodies/blood
  • Middle Aged
  • Opportunistic Infections/epidemiology
  • Portal Vein
  • Reproducibility of Results
  • Transplantation Conditioning/standards
Citation (ISO format)
SHAPIRO, A M James et al. International trial of the Edmonton protocol for islet transplantation. In: The New England journal of medicine, 2006, vol. 355, n° 13, p. 1318–1330. doi: 10.1056/NEJMoa061267
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
Journal ISSN0028-4793
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