Higher memory responses in HIV-infected and kidney transplanted patients than in healthy subjects following priming with the pandemic vaccine

Siegrist, Claire-Anne; Van Delden, Christian; Bel, Michael; Combescure, Christophe; Delhumeau-Cartier, Cécile; Cavassini, Matthias; Clerc, Olivier; Meier, Sara; Hadaya, Karine; Gasche-Soccal, Paola Marina Alessandra; Yerly Ferrillo, Sabine; Kaiser, Laurent; Hirschel, Bernard; Calmy, Alexandra; Swiss HIV cohort study

doi:10.1371/journal.pone.0040428

Scientific article

Open access

English

Higher memory responses in HIV-infected and kidney transplanted patients than in healthy subjects following priming with the pandemic vaccine

ContributorsSiegrist, Claire-Anne; Van Delden, Christian; Bel, Michael; Combescure, Christophe

; Delhumeau-Cartier, Cécile; Cavassini, Matthias; Clerc, Olivier; Meier, Sara; Hadaya, Karine; Gasche-Soccal, Paola Marina Alessandra; Yerly Ferrillo, Sabine; Kaiser, Laurent; Hirschel, Bernard; Calmy, Alexandra

; Swiss HIV cohort study

CollaboratorsPosfay Barbe, Klara; Grillet, Stéphane

Published inPloS one, vol. 7, no. 7, e40428

Publication date2012

Abstract

Memory responses require immune competence. We assessed the influence of priming with AS03-adjuvanted pandemic vaccine (Pandemrix®) on memory responses of HIV patients, kidney recipients (SOT) and healthy controls (HC).

Keywords

Adult
Aged
Antibodies, Viral/blood/immunology
Female
HIV Infections/blood/immunology
Humans
Immunocompromised Host
Immunologic Memory/drug effects
Influenza Vaccines/administration & dosage
Influenza, Human/blood/immunology/prevention & control
Kidney Transplantation/immunology
Male
Middle Aged
Pandemics

Affiliation

Research group

Citation (ISO format)

SIEGRIST, Claire-Anne et al. Higher memory responses in HIV-infected and kidney transplanted patients than in healthy subjects following priming with the pandemic vaccine. In: PloS one, 2012, vol. 7, n° 7, p. e40428. doi: 10.1371/journal.pone.0040428