Solid Phase Synthesis of Macrocycles by an Intramolecular Ketophosphonate Reaction. Synthesis of a (dl)-Muscone Library

Nicolaou, K. C.; Pastor, Joaquín; Winssinger, Nicolas; Murphy, Fiona

doi:10.1021/ja980675q

Scientific article

English

Solid Phase Synthesis of Macrocycles by an Intramolecular Ketophosphonate Reaction. Synthesis of a (dl)-Muscone Library

ContributorsNicolaou, K. C.; Pastor, Joaquín; Winssinger, Nicolas; Murphy, Fiona

Published inJournal of the American Chemical Society, vol. 120, no. 20, p. 5132-5133

Publication date1998

Abstract

The authors describe the construction of a muscone library using the powerful intramol. ketophosphonate-aldehyde condensation reaction. This adds another chem. to the solid-phase reaction library and demonstrates its power in the synthesis of natural products.

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

NICOLAOU, K. C. et al. Solid Phase Synthesis of Macrocycles by an Intramolecular Ketophosphonate Reaction. Synthesis of a (dl)-Muscone Library. In: Journal of the American Chemical Society, 1998, vol. 120, n° 20, p. 5132–5133. doi: 10.1021/ja980675q

Article (Published version)

Identifiers

PID : unige:24451
DOI : 10.1021/ja980675q

Journal ISSN0002-7863

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Solid Phase Synthesis of Macrocycles by an Intramolecular Ketophosphonate Reaction. Synthesis of a (dl)-Muscone Library

The authors describe the construction of a muscone library using the powerful intramol. ketophosphonate-aldehyde condensation reaction. This adds another chem. to the solid-phase reaction library and demonstrates its power in the synthesis of natural products.

Technical informations