Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide

Nicolaou, K. C.; Watanabe, Nobuhide; Li, Jim; Pastor, Joaquín; Winssinger, Nicolas

doi:10.1002/(SICI)1521-3773(19980619)37:11<1559::AID-ANIE1559>3.0.CO;2-E

Scientific article

English

Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide

ContributorsNicolaou, K. C.; Watanabe, Nobuhide; Li, Jim; Pastor, Joaquín; Winssinger, Nicolas

Published inAngewandte Chemie, vol. 37, no. 11, p. 1559-1561

Publication date1998

Abstract

Complicated oligosaccharides such as dodecasaccharide 1 can be constructed by a new solid-phase strategy. The attachment to the polymeric support (gray sphere) is through a photolabile linker (structure I), and thioglycosides serve as carbohydrate donors. Bn=benzyl, Bz=benzoyl.

Keywords

Block-type construction
Oligosaccharides
Photolabile linker
Solid-phase synthesis
Thioglycoside

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

NICOLAOU, K. C. et al. Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide. In: Angewandte Chemie, 1998, vol. 37, n° 11, p. 1559–1561. doi: 10.1002/(SICI)1521-3773(19980619)37:11<1559::AID-ANIE1559>3.0.CO;2-E

Article (Published version)

Identifiers

PID : unige:24447
DOI : 10.1002/(SICI)1521-3773(19980619)37:11<1559::AID-ANIE1559>3.0.CO;2-E

Journal ISSN1433-7851

515views

0downloads

Creation11/12/2012 15:40:00

First validation11/12/2012 15:40:00

Update time14/03/2023 18:46:57

Status update14/03/2023 18:46:57

Last indexation30/10/2024 09:02:28

Archive ouverte UNIGE

Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide

Complicated oligosaccharides such as dodecasaccharide 1 can be constructed by a new solid-phase strategy. The attachment to the polymeric support (gray sphere) is through a photolabile linker (structure I), and thioglycosides serve as carbohydrate donors. Bn=benzyl, Bz=benzoyl.

Technical informations