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Scientific article
Open access
English

Experimental Identification of Immuno- dominant B-cell Epitopes from SARS-CoV-2

Published inChimia, vol. 75, no. 4, p. 276-284
Publication date2021
Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the current public health crisis with devastating consequences to our societies. This COVID-19 pandemic has become the most serious threat to global public health in recent history. Given the unprecedented economic and social impact that it is causing, identification of immunodominant epitopes from SARS-CoV-2 is of great interest, not only to gain better insight into the adaptive immune response, but also for the development of vaccines, treatments and diagnostic tools. In this review, we summarize the already published or preprinted reports on the experimental identification of B-cell linear epitopes of SARS-CoV-2 proteins. Six different epitopes leading to neutralizing antibodies have been identified. Moreover, a summary of peptide candidates to be used for diagnostic tools is also included.

Research group
Citation (ISO format)
FARRERA SOLER, Lluc et al. Experimental Identification of Immuno- dominant B-cell Epitopes from SARS-CoV-2. In: Chimia, 2021, vol. 75, n° 4, p. 276–284. doi: 10.2533/chimia.2021.276
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ISSN of the journal0009-4293
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Creation04/28/2021 11:09:00 AM
First validation04/28/2021 11:09:00 AM
Update time03/16/2023 12:28:41 AM
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