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Critical Point in Self-Organized Tissue Growth

Publié dansPhysical Review Letters, vol. 120, no. 198102
Date de publication2018
Résumé

We present a theory of pattern formation in growing domains inspired by biological examples of tissue development. Gradients of signaling molecules regulate growth, while growth changes these graded chemical patterns by dilution and advection. We identify a critical point of this feedback dynamics, which is characterized by spatially homogeneous growth and proportional scaling of patterns with tissue length. We apply this theory to the biological model system of the developing wing of the fruit fly Drosophila melanogaster and quantitatively identify signatures of the critical point.

Citation (format ISO)
AGUILAR-HIDALGO, Daniel et al. Critical Point in Self-Organized Tissue Growth. In: Physical Review Letters, 2018, vol. 120, n° 198102. doi: 10.1103/PhysRevLett.120.198102
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ISSN du journal0031-9007
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Création22/09/2020 10:24:00
Première validation22/09/2020 10:24:00
Heure de mise à jour15/03/2023 22:38:23
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