Crucial role of aspartic acid at position 265 in the CH2 domain for murine IgG2a and IgG2b Fc-associated effector functions
Published inThe Journal of immunology, vol. 181, no. 9, p. 6664-6669
Publication date2008
Abstract
Keywords
- Alanine/genetics
- Amino Acid Substitution/genetics/physiology
- Anemia, Hemolytic, Autoimmune/genetics/immunology
- Animals
- Antibodies, Monoclonal/toxicity
- Aspartic Acid/genetics/physiology
- Autoantibodies/toxicity
- Complement Activation/genetics/immunology
- Erythrocytes/immunology
- Immunoglobulin G/chemistry/metabolism
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Knockout
- Protein Isoforms/chemistry/deficiency/genetics/physiology
- Protein Structure, Tertiary/genetics/physiology
- Receptors, Fc/chemistry/deficiency/genetics/physiology
- Sialic Acids/genetics
- Structure-Activity Relationship
Citation (ISO format)
BAUDINO, Lucie Clementine et al. Crucial role of aspartic acid at position 265 in the CH2 domain for murine IgG2a and IgG2b Fc-associated effector functions. In: The Journal of immunology, 2008, vol. 181, n° 9, p. 6664–6669. doi: 10.4049/jimmunol.181.9.6664
Main files (1)
Article (Accepted version)
Identifiers
- PID : unige:1395
- DOI : 10.4049/jimmunol.181.9.6664
- PMID : 18941257
Commercial URLhttp://www.jimmunol.org/cgi/content/full/181/9/6664
ISSN of the journal0022-1767