Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution

Rajaram, Renuga Devi; Dissard, Romain; Faivre, Anna; Ino, Frédérique; Delitsikou, Vasiliki; Jaquet, Vincent; Cagarelli, Thomas; Lindenmeyer, Maja; Jansen-Duerr, Pidder; Cohen, Clemens; Moll, Solange; De Seigneux Matthey, Sophie

doi:10.1016/j.redox.2019.101234

Article scientifique

Accès libre

Anglais

Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution

Contributeurs/tricesRajaram, Renuga Devi; Dissard, Romain; Faivre, Anna

; Ino, Frédérique; Delitsikou, Vasiliki; Jaquet, Vincent; Cagarelli, Thomas; Lindenmeyer, Maja; Jansen-Duerr, Pidder; Cohen, Clemens; Moll, Solange; De Seigneux Matthey, Sophie

Publié dansRedox Biology, vol. 26, 101234

Date de publication2019

Résumé

NADPH oxidase 4 (NOX4) catalyzes the formation of hydrogen peroxide (H2O2). NOX4 is highly expressed in the kidney, but its role in renal injury is unclear and may depend on its specific tissue localization.

Structure d'affiliation

Groupe de recherche

Financement

Swiss National Science Foundation - PP00P3 157454

Citation (format ISO)

RAJARAM, Renuga Devi et al. Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution. In: Redox Biology, 2019, vol. 26, p. 101234. doi: 10.1016/j.redox.2019.101234

Article (Published version)

CC BY-NC-ND

Identifiants

PID : unige:122903
DOI : 10.1016/j.redox.2019.101234
PMID : 31247506

ISSN du journal2213-2317

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Création03/09/2019 12:54:00

Première validation03/09/2019 12:54:00

Heure de mise à jour15/03/2023 17:59:26

Changement de statut15/03/2023 17:59:24

Dernière indexation12/02/2024 13:04:22

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Tubular NOX4 expression decreases in chronic kidney disease but does not modify fibrosis evolution

NADPH oxidase 4 (NOX4) catalyzes the formation of hydrogen peroxide (H2O2). NOX4 is highly expressed in the kidney, but its role in renal injury is unclear and may depend on its specific tissue localization.

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