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Antifungal diterpenes from Hypoestes serpens (Acanthaceae)

Rasoamiaranjanahari, L.
Marston, Andrew
Guilet, David
Schenk, K.
Randimbivololona, F.
Published in Phytochemistry. 2003, vol. 62, p. 333-337
Abstract Two new diterpenes, fusicoserperiol A and dolabeserpenoic acid A, with antifungal activity, were isolated from leaves of Hypoestes serpens (Acanthaceae). Their structures were elucidated by means of spectrometric methods including ID and 2D NMR experiments and MS analysis. X-ray crystallographic analysis confirmed the structure of fusicoserpenol A and established the relative configuration. (C) 2003 Elsevier Science Ltd. All rights reserved.
Keywords Hypoestes serpensAcanthaceaefusicoccanedolabellaneantifungal activityTERPENOIDSLIVERWORTSFORSKALEIKETONEROSEA
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