Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice
Published inGene therapy, vol. 5, no. 8, p. 1105-1113
Publication date1998
Abstract
Keywords
- Adenoviridae/ genetics
- Animals
- Breast Neoplasms/pathology/therapy
- Female
- Gene Therapy/ methods
- Genetic Engineering/methods
- Genetic Vectors/ administration & dosage
- Humans
- Injections, Intralesional
- Injections, Intramuscular
- Liver Neoplasms/secondary/therapy
- Lung Neoplasms/pathology/therapy
- Mice
- Mice, Inbred C57BL
- Neoplasm Transplantation
- Neoplasms/ therapy
- Neovascularization, Pathologic/ prevention & control
- Plasminogen Inactivators/pharmacology
- Rats
- Rats, Inbred Lew
- Receptors, Cell Surface/antagonists & inhibitors
- Receptors, Urokinase Plasminogen Activator
- Tumor Cells, Cultured
- Urokinase-Type Plasminogen Activator/antagonists & inhibitors/ genetics
Affiliation Not a UNIGE publication
Citation (ISO format)
LI, H. et al. Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice. In: Gene therapy, 1998, vol. 5, n° 8, p. 1105–1113. doi: 10.1038/sj.gt.3300742
Main files (1)
Article
Identifiers
- PID : unige:11423
- DOI : 10.1038/sj.gt.3300742
- PMID : 10326034
Commercial URLhttp://www.nature.com/gt/journal/v5/n8/pdf/3300742a.pdf
ISSN of the journal0969-7128