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Scientific article
English

Genetic engineering of embryonic stem cells

Published inSchweizerische medizinische Wochenschrift, vol. 136, no. 27-28, p. 413-415
Publication date2006
Abstract

We describe a novel generation of lentiviral vectors that are particularly well suited for work with embryonic stem cells. The possibility of selecting cell lines with antibiotics and the rapid insertion of any combination of promoters and genes of interest makes them a powerful tool in the generation of transgenic ES cell lines. This vector can also greatly facilitate studies aimed at the improvement of neuronal engineering from ES cells, by making it possible to monitor the emergence and differentiation of neurons.

Keywords
  • Animals
  • Cell Differentiation/genetics
  • Embryo, Mammalian/ cytology
  • Gene Expression
  • Genetic Engineering
  • Genetic Vectors/genetics
  • HIV/genetics
  • Humans
  • Neurons/transplantation
  • Stem Cell Transplantation
  • Stem Cells/physiology
Citation (ISO format)
SUTER, D. M., DUBOIS-DAUPHIN, Michel, KRAUSE, Karl-Heinz. Genetic engineering of embryonic stem cells. In: Schweizerische medizinische Wochenschrift, 2006, vol. 136, n° 27-28, p. 413–415.
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ISSN of the journal0036-7672
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