Scientific Article
previous document  unige:10861  next document
add to browser collection
Title

Sense and antisense transcription of bacteriophage T4 gene 32. Processing and stability of the mRNAs

Authors
Mudd, E. A.
Prentki, P.
Yi-Yi, Y.
Krisch, H. M.
Published in Journal of Molecular Biology. 1987, vol. 194, no. 2, p. 231-243
Abstract Analysis of bacteriophage T4 gene 32 transcription has revealed a multiplicity of mRNAs. In plasmids, gene 32 is expressed primarily from a strong promoter that is shut off after phage infection. In a wild-type infection, gene 32 is initially transcribed from prereplicative polycistronic and monocistronic promoters; subsequently, a monocistronic late mRNA predominates. This transcript, as well as a post-transcriptionally processed product of the earlier mRNA, can be stable. The eventual degradation of the stable mRNAs is temporally regulated by the phage. Finally, the transcription termination region of gene 32 can function as an antisense promoter both in vitro and in vivo.
Keywords Base SequenceGene ExpressionGenes, ViralPromoter Regions, GeneticRNA Processing, Post-Transcriptional/drug effectsRNA, Messenger/ geneticsRNA, Viral/ geneticsRifampin/pharmacologyT-Phages/ geneticsTranscription, Genetic
Stable URL http://archive-ouverte.unige.ch/unige:10861
Full text
This document has no fulltext available yet, but you can contact its author by using the form below.
Identifiers
PMID: 3612804
128 hits and 0 download since 2010-08-26
Update
Export document
Format :
Citation style :