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Title

Synaptic plasticity and dynamic modulation of the postsynaptic membrane

Authors
Nicoll, R. A.
Malenka, R. C.
Published in Nature Neuroscience. 2000, vol. 3, no. 6, p. 545-550
Abstract The biochemical composition of the postsynaptic membrane and the structure of dendritic spines may be rapidly modulated by synaptic activity. Here we review these findings, discuss their implications for long-term potentiation (LTP) and long-term depression (LTD) and propose a model of sequentially occurring expression mechanisms.
Keywords AnimalsCell SizeDendrites/ metabolismLong-Term Potentiation/ physiologyModels, NeurologicalNerve Tissue Proteins/metabolismNeural Inhibition/physiologyNeuronal Plasticity/ physiologyPseudopodia/metabolismReceptors, AMPA/metabolismSignal Transduction/physiologySynapses/ metabolismSynaptic Membranes/ metabolism
Stable URL http://archive-ouverte.unige.ch/unige:10347
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PMID: 10816309
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