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Title

Dynamic changes in brain activity during prism adaptation

Authors
Luaute, Jacques
Rossetti, Yves
Spiridon, Mona
Rode, Gilles
Boisson, Dominique
Published in Journal of Neuroscience. 2009, vol. 29, no. 1, p. 169-178
Abstract Prism adaptation does not only induce short-term sensorimotor plasticity, but also longer-term reorganization in the neural representation of space. We used event-related fMRI to study dynamic changes in brain activity during both early and prolonged exposure to visual prisms. Participants performed a pointing task before, during, and after prism exposure. Measures of trial-by-trial pointing errors and corrections allowed parametric analyses of brain activity as a function of performance. We show that during the earliest phase of prism exposure, anterior intraparietal sulcus was primarily implicated in error detection, whereas parieto-occipital sulcus was implicated in error correction. Cerebellum activity showed progressive increases during prism exposure, in accordance with a key role for spatial realignment. This time course further suggests that the cerebellum might promote neural changes in superior temporal cortex, which was selectively activated during the later phase of prism exposure and could mediate the effects of prism adaptation on cognitive spatial representations.
Keywords Adaptation, Physiological/ physiologyAdultBrain/anatomy & histology/blood supply/ physiologyBrain MappingFemaleFunctional LateralityHumansImage Processing, Computer-Assisted/methodsLensesMagnetic Resonance Imaging/methodsMaleNonlinear DynamicsOxygen/bloodPhotic Stimulation/methodsPsychomotor Performance/physiologyTime FactorsVisual Perception/physiologyYoung Adult
Stable URL http://archive-ouverte.unige.ch/unige:10341
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Other version: http://www.jneurosci.org/cgi/reprint/29/1/169.pdf
Identifiers
PMID: 19129395
Structures
Research groups Mécanismes cérébraux du comportement et des fonctions cognitives (701)
Neuroimagerie du Sommeil et de la Cognition (832)
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