Département de biochimie

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2016

Scientific Articles

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A 3D printed microfluidic device for production of functionalized hydrogel microcapsules for culture and differentiation of human Neuronal Stem Cells (hNSC)Alessandri, Kevin; Feyeux, Maxime; Gurchenkov, Basile; Delgado, Christophe; ... Roux, Aurélien
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A microfluidic cell-trapping device for single-cell tracking of host-microbe interactionsDelincé, Matthieu J; Bureau, Jean-Baptiste; Lopez Jimenez, Ana Teresa; Cosson, Pierre; ... McKinney, John D
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Dictyostelium EHD associates with Dynamin and participates in phagosome maturationGueho, Aurélie; Bosmani, Cristina; Gopaldass, Navin Andréw; Molle, Virginie; ... Letourneur, François
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Headgroup engineering in mechanosensitive membrane probesSoleimanpour, Saeideh; Colom Diego, Adai; Derivery, Emmanuel; Gonzalez Gaitan, Marcos; ... Matile, Stefan
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In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhASlepikas, Liudas; Chiriano, Gianpaolo; Perozzo, Remo; Tardy, Sébastien; ... Scapozza, Leonardo
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New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approachZufferey Bakos, Anne; Ibberson, Mark; Reny, Jean-Luc; Nolli, Severine; ... Fontana, Pierre
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Nucleic Acid Templated Chemical Reaction in a Live VertebrateHoltzer, Laurentius Henricus; Oleinich, Igor; Anzola, Marcello; Lindberg, Eric; ... Winssinger, Nicolas
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Of Amoebae and Men: Extracellular DNA Traps as an Ancient Cell-Intrinsic Defense MechanismZhang, Xuezhi; Soldati, Thierry;
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Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and BeyondVan Voorhis, Wesley C; Adams, John H; Adelfio, Roberto; Ahyong, Vida; ... Willis, Paul A
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Selective Imaging of Late Endosomes with a pH-Sensitive Diazaoxatriangulene Fluorescent ProbeWallabregue, Antoine; Moreau, Dimitri; Sherin, Petr; Moneva Lorente, Pau; ... Lacour, Jérôme
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Social amoebae trap and kill bacteria by casting DNA netsZhang, Xuezhi; Zhuchenko, Olga; Kuspa, Adam; Soldati, Thierry;
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WASH drives early recycling from macropinosomes and phagosomes to maintain surface phagocytic receptorsBuckley, Catherine M; Gopaldass, Navin Andréw; Bosmani, Cristina; Johnston, Simon A; ... King, Jason S

Doctoral Thesis

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Analysis of mechanisms that control the onset of neurogenesis in the avian retinasRodrigues, Tania;
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Dpp signalling gradient scaling and cell size regulation in Drosophila wing imaginal discsMachado, Sarah;
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Regulation of dynamin-mediated membrane fission by the N-BAR protein endophilinHohendahl, Annika;
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Visualizing the GTPase activity of dynamin with nanobodiesGalli, Valentina;

2015

Scientific Articles

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Adrenergic antagonists restrict replication of LegionellaHarrison, Christopher F; Kicka, Sébastien; Kranjc Pietrucci, Agata; Finsel, Ivo; ... Hilbi, Hubert
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Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophilaHarrison, Christopher F.; Chiriano, Gianpaolo; Finsel, Ivo; Manske, Christian; ... Hilbi, Hubert
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Cell-penetrating poly(disulfide)s: the dependence of activity, depolymerization kinetics and intracellular localization on their lengthChuard, Nicolas; Gasparini, Giulio; Roux, Aurélien; Sakai, Naomi; Matile, Stefan
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Charged Solvatochromic Dyes as Signal Transducers in pH Independent Fluorescent and Colorimetric Ion Selective NanosensorsXie, Xiaojiang; Gutierrez, Agustin; Trofimov, Valentin; Szilagyi, Istvan; ... Bakker, Eric
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De novo isolation of antibodies with pH-dependent binding propertiesBonvin, Pauline; Venet, Sophie; Fontaine, Gaëlle; Ravn, Ulla; ... Fischer, Nicolas
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Enantioselective Halogenative Semi-Pinacol Rearrangement: Extension of Substrate Scope and Mechanistic InvestigationsRomanov Michailidis, Fedor; Romanova Michailidi, Maria; Pupier, Marion; Alexakis, Alexandre;
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Fluorescent Flippers for Mechanosensitive Membrane ProbesDal Molin, Marta; Verolet, Quentin; Colom Diego, Adai; Letrun, Romain; ... Matile, Stefan
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Lipid droplet dynamics at early stages of Mycobacterium marinum infection in DictyosteliumBarisch, Caroline; Paschke, Peggy; Hagedorn, Monica; Maniak, Markus; Soldati, Thierry
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Live imaging of Mycobacterium marinum infection in Dictyostelium discoideumBarisch, Caroline; Lopez Jimenez, Ana Teresa; Soldati, Thierry;
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Potassium Sensitive Optical Nanosensors Containing Voltage Sensitive DyesXie, Xiaojiang; Gutierrez, Agustin; Trofimov, Valentin; Szilagyi, Istvan; ... Bakker, Eric
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Reactive oxygen species and mitochondria: A nexus of cellular homeostasisDunn, Joe Dan; Alvarez, Luis AJ; Zhang, Xuezhi; Soldati, Thierry;
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The autophagic machinery ensures nonlytic transmission of mycobacteriaGerstenmaier, Lilli; Pilla, Rachel; Herrmann, Lydia; Herrmann, Hendrik; ... Hagedorn, Monica
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The Human Diabetes Proteome Project (HDPP): The 2014 updateSchvartz, Domitille; Bergsten, Peter; Baek, Kwang Hyun; Barba de la Rosa, Ana Paulina; ... Sanchez, Jean-Charles

Doctoral Thesis

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Mechanism of Dpp transport and Dpp gradient scaling in the wing imaginal disc of Drosophila MelanogasterRomanova Michailidi, Maria;
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Metabolic control of cell adhesion and migration through beta1A integrin acetylation : be aware of the acetylation switch!Kastberger, Birgit;
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Therapeutic targeting of promiscuous and abundant chemokinesBonvin, Pauline;

2014

Scientific Articles

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A genomic perspective on a new bacterial genus and species from the Alcaligenaceae family, Basilea psittacipulmonisWhiteson, Katrine L; Hernandez, David; Lazarevic, Vladimir; Gaia, Nadia; ... Schrenzel, Jacques
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Cellular Uptake of Substrate-Initiated Cell-Penetrating Poly(disulfide)sGasparini, Giulio; Bang, Eun Kyoung; Molinard, Guillaume; Tulumello, David V.; ... Matile, Stefan
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Conditional Depletion of the Chlamydomonas Chloroplast ClpP Protease Activates Nuclear Genes Involved in Autophagy and Plastid Protein Quality ControlRamundo, Silvia; Casero, David; Mühlhaus, Timo; Hemme, Dorothea; ... Rochaix, Jean-David
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Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen systemKicka, Sébastien; Trofimov, Valentin; Harrison, Christopher; Ouertatani, Hajer; ... Soldati, Thierry
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Identification of the pharmacophore of the CC chemokine-binding proteins Evasin-1 and -4 using phage displayBonvin, Pauline; Dunn, Steven M; Rousseau, François; Dyer, Douglas; ... Proudfoot, Amanda

Doctoral Thesis

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A kinome-wide RNAi screen to identify genes controlling membrane lipid homeostasis in human cellsGehin, Charlotte;
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Integrated approach for the characterization of the predicted human deoxyribose phosphate aldolaseSalleron, Lisa;
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New Inisgths on Lipid Homeostasis: Systematic Lipidomics of a Yeast Knockout Collection of Genes of Protein Kinases and PhosphatasesXavier Da Silveira Dos Sa, Aline;
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The intracellular transport of glycosylphosphatidylinositol-anchored proteins in mammalian Chinese Hamster Ovary cellsJaensch, Nina;

2013

Scientific Articles

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A Positive Feedback Loop between ATOH7 and a Notch Effector Regulates Cell-Cycle Progression and Neurogenesis in the RetinaChiodini, Florence; Matter-Sadzinski, Lidia; Rodrigues, Tania; Skowronska-Krawczyk, Dorota; ... Matter, Jean-Marc
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CCL18 exhibits a regulatory role through inhibition of receptor and glycosaminoglycan bindingKrohn, Sonja; Bonvin, Pauline; Proudfoot, Amanda E.I.;
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Detecting, visualizing and quantitating the generation of reactive oxygen species in an amoeba model systemZhang, Xuezhi; Soldati, Thierry;
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Evasin-4, a tick-derived chemokine-binding protein with broad selectivity can be modified for use in preclinical disease modelsDeruaz, Maud; Bonvin, Pauline; Severin, India C; Johnson, Zoë; ... Proudfoot, Amanda E I
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Exploring Anti-Bacterial Compounds against Intracellular LegionellaHarrison, Christopher F; Kicka, Sébastien; Trofimov, Valentin; Berschl, Kathrin; ... Hilbi, Hubert
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Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in micePitetti, Jean-Luc; Calvel, Pierre; Romero, Yannick; Conne, Béatrice; ... Nef, Serge
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Substrate-Initiated Synthesis of Cell-Penetrating Poly(disulfide)sBang, Eun Kyoung; Gasparini, Giulio; Molinard, Guillaume; Roux, Aurélien; ... Matile, Stefan
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WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestionKing, Jason S; Gueho, Aurélie; Hagedorn, Monica; Gopaldass, Navin Andréw; ... Insall, Robert H

Doctoral Thesis

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Endocytosis, Sara and cell fate decisions during asymmetric stem cell division in the adult Drosophila midgutMontagne, Chrystelle;
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Proteomic characterisation of the Mycobacterium marinum-containing compartment in Dictyostelium discoideumGueho, Aurélie;
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Study of reactive oxygen species and NADPH oxidases in an amoeba model systemZhang, Xuezhi;

2012

Scientific Articles

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Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cellsEpstein, Sharon; Kirkpatrick, Clare; Castillon, Guillaume Alain; Muniz, Manuel; ... Riezman, Howard
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Dynamin A, Myosin IB and Abp1 couple phagosome maturation to F-actin bindingGopaldass, Navin Andréw; Patel, Devang; Kratzke, Ramona; Dieckmann, Régis; ... Soldati, Thierry
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Guidelines for the use and interpretation of assays for monitoring autophagyKlionsky, Daniel J; Buzgariu, Wanda Christa; Galliot, Brigitte; Scorrano, Luca; Soldati, Thierry
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Mucolipin controls lysosome exocytosis in DictyosteliumLima, Wanessa C; Leuba, Florence; Soldati, Thierry; Cosson, Pierre;
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Mycobacteria and the intraphagosomal environment: take it with a pinch of salt(s)!Soldati, Thierry; Neyrolles, Olivier;
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Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesisBerchtold, Doris; Piccolis, Manuele; Chiaruttini, Nicolas; Riezman, Isabelle; ... Loewith, Robbie Joséph
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Rab8a regulates the exocyst-mediated kiss-and-run discharge of the Dictyostelium contractile vacuoleEssid, Miriam; Gopaldass, Navin Andréw; Yoshida, Kunito; Merrifield, Christien; Soldati, Thierry
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Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime moldsJaiswal, Pundrik; Soldati, Thierry; Thewes, Sascha; Baskar, Ramamurthy;
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SNX12 Role in Endosome Membrane TransportPons, Véronique; Ustunel Eren, Cansel; Rolland, Corinne; Torti, Eleonora; ... Gruenberg, Jean
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The Balance in the Delivery of ER Components and the Vacuolar Proton Pump to the Phagosome Depends on Myosin IK in DictyosteliumDieckmann, Régis; Gueho, Aurélie; Monroy, Roger; Ruppert, Thomas; ... Soldati, Thierry
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The cutaneous lesions of dioxin exposure: lessons from the poisoning of Victor YushchenkoSaurat, Jean-Hilaire; Kaya, Guerkan; Saxer-sekulic, Nikolina; Pardo, Bruno; ... Sorg, Olivier

Book Chapters

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How One Cell Eats Another : Principles of PhagocytosisTollis, Sylvain; Gopaldass, Navin; Soldati, Thierry; Endres, Robert G.;

Doctoral Thesis

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Analysis of new potential markers for the immediate evalua-tion of electrochemotherapy using small animal imagingRaeisi, Elham;
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Characterization of HIV-1 host interactions by advanced fluorescence microscopyLehmann, Martin;
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Dynamin-mediated membrane fissionMorlot, Sandrine;
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Probing atypical chemokine biologyKrohn, Sonja;
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Regulation of IL-17ARoller, Anne;
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Role of the scavenger receptor class B members LmpA, LmpB and LmpC during phagocytosis and phagosome maturationSattler, Natascha;
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The multiple physiological roles of the lipid ceramide in the yeast Saccharomyces cerevisiaeEpstein, Sharon;
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The role of SARA1 Endosomes during neural precursor fate assignationKressmann, Sabine;
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Viral infection controlled by a novel calcium-dependent lipid-binding module in AlixBissig, Christin;

2010

Scientific Articles

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A myosin IK-Abp1-PakB circuit acts as a switch to regulate phagocytosis efficiencyDieckmann, Régis; von Heyden, Yosuke; Kistler, Claudia; Gopaldass, Navin Andréw; ... Soldati, Thierry
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Autophagy in Dictyostelium: genes and pathways, cell death and infectionCalvo-Garrido, Javier; Carilla-Latorre, Sergio; Kubohara, Yuzuru; Santos-Rodrigo, Natalia; ... Escalante, Ricardo
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Mitochondrial translation in absence of local tRNA aminoacylation and methionyl tRNA formylation in ApicomplexaPino, Paco; Aeby, Eric; Foth, Bernardo Javier; Sheiner, Lilach; ... Soldati-Favre, Dominique
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Molecular characterization of the evolution of phagosomesBoulais, Jonathan; Trost, Matthias; Landry, Christian R; Dieckmann, Régis; ... Desjardins, Michel

Doctoral Thesis

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Control of proliferation by the Dpp gradient in the wing imaginal disc of Drosophila melanogasterWartlick, Ortrud;
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DE HIF-1 alpha/FOXO aux canaux KATP : une nouvelle voie de signalisation potentiellement cardioprotectrice chez l'enfant souffrant d'hypoxémie veineuseRaeis, Véronique;
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IL-1β and sIL-1Ra Production in acute and chronic inflammation : regulation and signaling in human monocytesBrandt, Karim;
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Role of LRH-1/NR5A2 in islet physiology and pathophysiologyBaquie, Mathurin;
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The interplay between endosomal sorting of the epidermal growth factor receptor and signalingBrankatschk, Ben;
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The role of Interleukin-6 in nervous regeneration and functional recovery in organotypic hippocampal slice culturesHakkoum, David;
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